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Page 1
Risks of Iodine Excess.
Sohn SY, Inoue K, Rhee CM, Leung AM. Sohn SY, et al. Endocr Rev. 2024 Nov 22;45(6):858-879. doi: 10.1210/endrev/bnae019. Endocr Rev. 2024. PMID: 38870258 Free article. Review.
Although excessive iodine intake or exposure is generally well tolerated, an acute iodine load may result in thyroid dysfunction (hypothyroidism or hyperthyroidism) in certain susceptible individuals due to the failure to escape from the Wolff- …
Although excessive iodine intake or exposure is generally well tolerated, an acute iodine load may result in thyroid …
Iodine-Induced hypothyroidism.
Markou K, Georgopoulos N, Kyriazopoulou V, Vagenakis AG. Markou K, et al. Thyroid. 2001 May;11(5):501-10. doi: 10.1089/105072501300176462. Thyroid. 2001. PMID: 11396709 Review.
Iodine is an essential element for thyroid hormone synthesis. The thyroid gland has the capacity and holds the machinery to handle the iodine efficiently when the availability of iodine becomes scarce, as well as when iodine is ava …
Iodine is an essential element for thyroid hormone synthesis. The thyroid gland has the capacity and holds the m …
Iodine excess.
Bürgi H. Bürgi H. Best Pract Res Clin Endocrinol Metab. 2010 Feb;24(1):107-15. doi: 10.1016/j.beem.2009.08.010. Best Pract Res Clin Endocrinol Metab. 2010. PMID: 20172475 Review.
The sodium-iodide symporter system contributes most to this stability. Faced with an iodine excess, it throttles the transport of iodide into the thyroid cells, the rate-limiting step of hormone synthesis. ...These autonomous nodules gradually disappear from …
The sodium-iodide symporter system contributes most to this stability. Faced with an iodine excess, it throttles the transport …
Effect of excess iodine intake on thyroid on human health.
Koukkou EG, Roupas ND, Markou KB. Koukkou EG, et al. Minerva Med. 2017 Apr;108(2):136-146. doi: 10.23736/S0026-4806.17.04923-0. Epub 2017 Jan 12. Minerva Med. 2017. PMID: 28079354 Review.
The thyroid gland has several protective mechanisms resulting on the maintenance of normal thyroid function despite wide fluctuations of the daily iodine intake. ...Iodine excess may also establish a status of excessive thyroid …
The thyroid gland has several protective mechanisms resulting on the maintenance of normal thyroid function despite wid …
Hyperthyroidism (Nursing).
Mathew P, Kaur J, Rawla P, Fortes K. Mathew P, et al. 2023 Mar 19. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2023 Mar 19. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 33760541 Free Books & Documents.
Histologically, the thyroid gland is surrounded by a thin, connective tissue covering that penetrates the gland and divides the thyroid gland into compartments. ...Most of the conversion of T4 to T3 occurs outside the thyroid, although th …
Histologically, the thyroid gland is surrounded by a thin, connective tissue covering that penetrates the gland and div …
Critical Role of Iodine and Thyroid Hormones During Pregnancy.
Moreno-Reyes R, Fuentes Peña C, Nuñez JF, Sánchez MB, Carvajal JJ, Roble K, Mendoza-León MJ, Rangel-Ramírez MA, Opazo MC, Lay MK, Riedel CA, Guzmán-Gutierrez E, Mackern-Oberti JP, Jara EL. Moreno-Reyes R, et al. Int J Mol Sci. 2025 Oct 22;26(21):10247. doi: 10.3390/ijms262110247. Int J Mol Sci. 2025. PMID: 41226288 Free PMC article. Review.
Iodine is an essential micronutrient that is required for thyroid hormone (TH) synthesis. ...Conversely, excessive iodine intake may impair fetal thyroid function through mechanisms such as the Wolff-Chaikoff effect. ...
Iodine is an essential micronutrient that is required for thyroid hormone (TH) synthesis. ...Conversely, excessive i …
Iodine-Induced Hypothyroidism After Chemoembolization With Ethiodized Oil: A Case of Failure to Escape From Wolff-Chaikoff Effect (WCE).
Campos AC, Cruz Carvalho I, Sarmento S, Fonseca T. Campos AC, et al. Cureus. 2023 May 22;15(5):e39352. doi: 10.7759/cureus.39352. eCollection 2023 May. Cureus. 2023. PMID: 37351229 Free PMC article.
Wolff-Chaikoff effect (WCE) is an acute physiologic response of the thyroid gland to high levels of iodine. The WCE is usually temporary, and the thyroid gland adjusts to high iodine levels within days or weeks. It is a prot …
Wolff-Chaikoff effect (WCE) is an acute physiologic response of the thyroid gland to high levels of iodine …
[Iodine excess induced thyroid dysfunction].
Egloff M, Philippe J. Egloff M, et al. Rev Med Suisse. 2016 Apr 20;12(515):804-9. Rev Med Suisse. 2016. PMID: 27276725 French.
The principle sources of iodine overload, amiodarone and radiologic contrast media, are frequently used in modern medicine. The thyroid gland exerts a protective effect against iodine excess by suppressing iodine internalization into the …
The principle sources of iodine overload, amiodarone and radiologic contrast media, are frequently used in modern medicine. The th …
Escape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid sodium/iodide symporter messenger ribonucleic acid and protein.
Eng PH, Cardona GR, Fang SL, Previti M, Alex S, Carrasco N, Chin WW, Braverman LE. Eng PH, et al. Endocrinology. 1999 Aug;140(8):3404-10. doi: 10.1210/endo.140.8.6893. Endocrinology. 1999. PMID: 10433193
Our findings support the hypothesis that the escape from the acute Wolff-Chaikoff effect is caused by a decrease in NIS, with a resultant decreased iodide transport into the thyroid. The observed decrease in TPO mRNA may contribute to the iodine-induce …
Our findings support the hypothesis that the escape from the acute Wolff-Chaikoff effect is caused by a decrease in NIS, with …
Iodine and thyroid disease.
Woeber KA. Woeber KA. Med Clin North Am. 1991 Jan;75(1):169-78. doi: 10.1016/s0025-7125(16)30477-1. Med Clin North Am. 1991. PMID: 1987441
An autoregulatory mechanism within the thyroid serves as the first line of defense against fluctuations in the supply of iodine and also permits escape from the inhibition of hormone synthesis that a very large quantity of iodine induces (Wolff-Chai …
An autoregulatory mechanism within the thyroid serves as the first line of defense against fluctuations in the supply of iodine …
39 results