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Single HA2 mutation increases the infectivity and immunogenicity of a live attenuated H5N1 intranasal influenza vaccine candidate lacking NS1.
Krenn BM, Egorov A, Romanovskaya-Romanko E, Wolschek M, Nakowitsch S, Ruthsatz T, Kiefmann B, Morokutti A, Humer J, Geiler J, Cinatl J, Michaelis M, Wressnigg N, Sturlan S, Ferko B, Batishchev OV, Indenbom AV, Zhu R, Kastner M, Hinterdorfer P, Kiselev O, Muster T, Romanova J. Krenn BM, et al. Among authors: wolschek m. PLoS One. 2011 Apr 7;6(4):e18577. doi: 10.1371/journal.pone.0018577. PLoS One. 2011. PMID: 21490925 Free PMC article.
Preclinical evaluation of a replication-deficient intranasal DeltaNS1 H5N1 influenza vaccine.
Romanova J, Krenn BM, Wolschek M, Ferko B, Romanovskaja-Romanko E, Morokutti A, Shurygina AP, Nakowitsch S, Ruthsatz T, Kiefmann B, König U, Bergmann M, Sachet M, Balasingam S, Mann A, Oxford J, Slais M, Kiselev O, Muster T, Egorov A. Romanova J, et al. Among authors: wolschek m. PLoS One. 2009 Jun 19;4(6):e5984. doi: 10.1371/journal.pone.0005984. PLoS One. 2009. PMID: 19543385 Free PMC article.
A novel type of influenza vaccine: safety and immunogenicity of replication-deficient influenza virus created by deletion of the interferon antagonist NS1.
Wacheck V, Egorov A, Groiss F, Pfeiffer A, Fuereder T, Hoeflmayer D, Kundi M, Popow-Kraupp T, Redlberger-Fritz M, Mueller CA, Cinatl J, Michaelis M, Geiler J, Bergmann M, Romanova J, Roethl E, Morokutti A, Wolschek M, Ferko B, Seipelt J, Dick-Gudenus R, Muster T. Wacheck V, et al. Among authors: wolschek m. J Infect Dis. 2010 Feb 1;201(3):354-62. doi: 10.1086/649428. J Infect Dis. 2010. PMID: 20039806 Clinical Trial.
37 results