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Single center, open label dose escalating trial evaluating once weekly oral ixazomib in ART-suppressed, HIV positive adults and effects on HIV reservoir size in vivo.
Cummins NW, Baker J, Chakraborty R, Dean PG, Garcia-Rivera E, Krogman A, Kumar S, Kuzmichev YV, Laird GM, Landay A, Lichterfeld M, Mahmood M, Martinson J, Maynes M, Natesampillai S, Rajkumar V, Rassadkina Y, Ritter KD, Rivera CG, Rizza SA, Subramanian K, Tande AJ, Wonderlich ER, Whitaker JA, Zeuli J, Badley AD. Cummins NW, et al. Among authors: wonderlich er. EClinicalMedicine. 2021 Nov 29;42:101225. doi: 10.1016/j.eclinm.2021.101225. eCollection 2021 Dec. EClinicalMedicine. 2021. PMID: 34901797 Free PMC article.
Inhibitors of HIV-1 Nef-Mediated Activation of the Myeloid Src-Family Kinase Hck Block HIV-1 Replication in Macrophages and Disrupt MHC-I Downregulation.
Emert-Sedlak LA, Moukha-Chafiq O, Shi H, Du S, Alvarado JJ, Pathak V, Tanner SG, Hunter RN, Nebane M, Chen L, Ilina TV, Ishima R, Zhang S, Kuzmichev YV, Wonderlich ER, Schader SM, Augelli-Szafran CE, Ptak RG, Smithgall TE. Emert-Sedlak LA, et al. Among authors: wonderlich er. ACS Infect Dis. 2022 Jan 14;8(1):91-105. doi: 10.1021/acsinfecdis.1c00288. Epub 2022 Jan 5. ACS Infect Dis. 2022. PMID: 34985256 Free PMC article.
Novel Compound Inhibitors of HIV-1NL4-3 Vpu.
Robinson CA, Lyddon TD, Gil HM, Evans DT, Kuzmichev YV, Richard J, Finzi A, Welbourn S, Rasmussen L, Nebane NM, Gupta VV, Ananthan S, Cai Z, Wonderlich ER, Augelli-Szafran CE, Bostwick R, Ptak RG, Schader SM, Johnson MC. Robinson CA, et al. Among authors: wonderlich er. Viruses. 2022 Apr 15;14(4):817. doi: 10.3390/v14040817. Viruses. 2022. PMID: 35458546 Free PMC article.
Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals.
Wonderlich ER, Subramanian K, Cox B, Wiegand A, Lackman-Smith C, Bale MJ, Stone M, Hoh R, Kearney MF, Maldarelli F, Deeks SG, Busch MP, Ptak RG, Kulpa DA. Wonderlich ER, et al. PLoS Pathog. 2019 Oct 14;15(10):e1008074. doi: 10.1371/journal.ppat.1008074. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31609991 Free PMC article.
A highly multiplexed droplet digital PCR assay to measure the intact HIV-1 proviral reservoir.
Levy CN, Hughes SM, Roychoudhury P, Reeves DB, Amstuz C, Zhu H, Huang ML, Wei Y, Bull ME, Cassidy NAJ, McClure J, Frenkel LM, Stone M, Bakkour S, Wonderlich ER, Busch MP, Deeks SG, Schiffer JT, Coombs RW, Lehman DA, Jerome KR, Hladik F. Levy CN, et al. Among authors: wonderlich er. Cell Rep Med. 2021 Apr 12;2(4):100243. doi: 10.1016/j.xcrm.2021.100243. eCollection 2021 Apr 20. Cell Rep Med. 2021. PMID: 33948574 Free PMC article.
Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection.
Lee MY, Upadhyay AA, Walum H, Chan CN, Dawoud RA, Grech C, Harper JL, Karunakaran KA, Nelson SA, Mahar EA, Goss KL, Carnathan DG, Cervasi B, Gill K, Tharp GK, Wonderlich ER, Velu V, Barratt-Boyes SM, Paiardini M, Silvestri G, Estes JD, Bosinger SE. Lee MY, et al. Among authors: wonderlich er. PLoS Pathog. 2021 Jun 28;17(6):e1009674. doi: 10.1371/journal.ppat.1009674. eCollection 2021 Jun. PLoS Pathog. 2021. PMID: 34181694 Free PMC article.
25 results