Wong AS - Search Results

1

Massively parallel high-order combinatorial genetics in human cells.

Wong AS, Choi GC, Cheng AA, Purcell O, Lu TK. Wong AS, et al. Nat Biotechnol. 2015 Sep;33(9):952-61. doi: 10.1038/nbt.3326. Epub 2015 Aug 17. Nat Biotechnol. 2015. PMID: 26280411 Free PMC article.

2

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

Wong AS, Choi GC, Cui CH, Pregernig G, Milani P, Adam M, Perli SD, Kazer SW, Gaillard A, Hermann M, Shalek AK, Fraenkel E, Lu TK. Wong AS, et al. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2544-9. doi: 10.1073/pnas.1517883113. Epub 2016 Feb 10. Proc Natl Acad Sci U S A. 2016. PMID: 26864203 Free PMC article.

3

Deciphering Combinatorial Genetics.

Wong AS, Choi GC, Lu TK. Wong AS, et al. Annu Rev Genet. 2016 Nov 23;50:515-538. doi: 10.1146/annurev-genet-120215-034902. Epub 2016 Oct 6. Annu Rev Genet. 2016. PMID: 27732793 Review.

4

Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9.

Choi GCG, Zhou P, Yuen CTL, Chan BKC, Xu F, Bao S, Chu HY, Thean D, Tan K, Wong KH, Zheng Z, Wong ASL. Choi GCG, et al. Nat Methods. 2019 Aug;16(8):722-730. doi: 10.1038/s41592-019-0473-0. Epub 2019 Jul 15. Nat Methods. 2019. PMID: 31308554

5

Publisher Correction: Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9.

Choi GCG, Zhou P, Yuen CTL, Chan BKC, Xu F, Bao S, Chu HY, Thean D, Tan K, Wong KH, Zheng Z, Wong ASL. Choi GCG, et al. Nat Methods. 2019 Aug;16(8):789. doi: 10.1038/s41592-019-0533-5. Nat Methods. 2019. PMID: 31337886

6

A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets.

Zhou P, Chan BKC, Wan YK, Yuen CTL, Choi GCG, Li X, Tong CSW, Zhong SSW, Sun J, Bao Y, Mak SYL, Chow MZY, Khaw JV, Leung SY, Zheng Z, Cheung LWT, Tan K, Wong KH, Chan HYE, Wong ASL. Zhou P, et al. Cell Rep. 2020 Aug 11;32(6):108020. doi: 10.1016/j.celrep.2020.108020. Cell Rep. 2020. PMID: 32783942 Free article.

7

High-Throughput Protein Engineering by Massively Parallel Combinatorial Mutagenesis.

Wan YK, Choi GCG, Wong ASL. Wan YK, et al. Methods Mol Biol. 2021;2199:3-12. doi: 10.1007/978-1-0716-0892-0_1. Methods Mol Biol. 2021. PMID: 33125641

8

Extensible combinatorial CRISPR screening in mammalian cells.

Zhou P, Wan YK, Chan BKC, Choi GCG, Wong ASL. Zhou P, et al. STAR Protoc. 2021 Jan 9;2(1):100255. doi: 10.1016/j.xpro.2020.100255. eCollection 2021 Mar 19. STAR Protoc. 2021. PMID: 33490975 Free PMC article.

9

High-throughput 5' UTR engineering for enhanced protein production in non-viral gene therapies.

Cao J, Novoa EM, Zhang Z, Chen WCW, Liu D, Choi GCG, Wong ASL, Wehrspaun C, Kellis M, Lu TK. Cao J, et al. Nat Commun. 2021 Jul 6;12(1):4138. doi: 10.1038/s41467-021-24436-7. Nat Commun. 2021. PMID: 34230498 Free PMC article.

10

A Combinatorial CRISPR-Cas9 Screen Identifies Ifenprodil as an Adjunct to Sorafenib for Liver Cancer Treatment.

Xu F, Tong M, Tong CSW, Chan BKC, Chu HY, Wong TL, Fong JHC, Cheung MSH, Mak KH, Pardeshi L, Huang Y, Wong KH, Choi GCG, Ma S, Wong ASL. Xu F, et al. Cancer Res. 2021 Dec 15;81(24):6219-6232. doi: 10.1158/0008-5472.CAN-21-1017. Epub 2021 Oct 19. Cancer Res. 2021. PMID: 34666996

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