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Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients.
Gillespie J, Savic S, Wong C, Hempshall A, Inman M, Emery P, Grigg R, McDermott MF. Gillespie J, et al. Among authors: wong c. Arthritis Rheum. 2012 Feb;64(2):418-22. doi: 10.1002/art.33382. Arthritis Rheum. 2012. PMID: 21952924 Free article.
Involvement of X-box binding protein 1 and reactive oxygen species pathways in the pathogenesis of tumour necrosis factor receptor-associated periodic syndrome.
Dickie LJ, Aziz AM, Savic S, Lucherini OM, Cantarini L, Geiler J, Wong CH, Coughlan R, Lane T, Lachmann HJ, Hawkins PN, Robinson PA, Emery P, McGonagle D, McDermott MF. Dickie LJ, et al. Ann Rheum Dis. 2012 Dec;71(12):2035-43. doi: 10.1136/annrheumdis-2011-201197. Epub 2012 Jun 7. Ann Rheum Dis. 2012. PMID: 22679299
Differential effects of infliximab on absolute circulating blood leucocyte counts of innate immune cells in early and late rheumatoid arthritis patients.
Coulthard LR, Geiler J, Mathews RJ, Church LD, Dickie LJ, Cooper DL, Wong C, Savic S, Bryer D, Buch MH, Emery P, Morgan AW, McDermott MF. Coulthard LR, et al. Among authors: wong c. Clin Exp Immunol. 2012 Oct;170(1):36-46. doi: 10.1111/j.1365-2249.2012.04626.x. Clin Exp Immunol. 2012. PMID: 22943199 Free PMC article. Clinical Trial.
Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.
Mathews RJ, Robinson JI, Battellino M, Wong C, Taylor JC; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS); Eyre S, Churchman SM, Wilson AG, Isaacs JD, Hyrich K, Barton A, Plant D, Savic S, Cook GP, Sarzi-Puttini P, Emery P, Barrett JH, Morgan AW, McDermott MF. Mathews RJ, et al. Among authors: wong c. Ann Rheum Dis. 2014 Jun;73(6):1202-10. doi: 10.1136/annrheumdis-2013-203276. Epub 2013 May 17. Ann Rheum Dis. 2014. PMID: 23687262
Inositol-Requiring Enzyme 1-Mediated Downregulation of MicroRNA (miR)-146a and miR-155 in Primary Dermal Fibroblasts across Three TNFRSF1A Mutations Results in Hyperresponsiveness to Lipopolysaccharide.
Harrison SR, Scambler T, Oubussad L, Wong C, Wittmann M, McDermott MF, Savic S. Harrison SR, et al. Among authors: wong c. Front Immunol. 2018 Feb 6;9:173. doi: 10.3389/fimmu.2018.00173. eCollection 2018. Front Immunol. 2018. PMID: 29467762 Free PMC article.
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