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A soluble single-chain T-cell receptor IL-2 fusion protein retains MHC-restricted peptide specificity and IL-2 bioactivity.
Card KF, Price-Schiavi SA, Liu B, Thomson E, Nieves E, Belmont H, Builes J, Jiao JA, Hernandez J, Weidanz J, Sherman L, Francis JL, Amirkhosravi A, Wong HC. Card KF, et al. Among authors: wong hc. Cancer Immunol Immunother. 2004 Apr;53(4):345-57. doi: 10.1007/s00262-003-0450-3. Epub 2003 Nov 11. Cancer Immunol Immunother. 2004. PMID: 14610621
Potent antitumor activity of a tumor-specific soluble TCR/IL-2 fusion protein.
Belmont HJ, Price-Schiavi S, Liu B, Card KF, Lee HI, Han KP, Wen J, Tang S, Zhu X, Merrill J, Chavillaz PA, Wong JL, Rhode PR, Wong HC. Belmont HJ, et al. Among authors: wong hc, wong jl. Clin Immunol. 2006 Oct;121(1):29-39. doi: 10.1016/j.clim.2006.05.005. Epub 2006 Jun 30. Clin Immunol. 2006. PMID: 16807113
Targeting activity of a TCR/IL-2 fusion protein against established tumors.
Wen J, Zhu X, Liu B, You L, Kong L, Lee HI, Han KP, Wong JL, Rhode PR, Wong HC. Wen J, et al. Among authors: wong hc, wong jl. Cancer Immunol Immunother. 2008 Dec;57(12):1781-94. doi: 10.1007/s00262-008-0504-7. Epub 2008 Mar 28. Cancer Immunol Immunother. 2008. PMID: 18369620
Inhibition of acute vascular thrombosis in chimpanzees by an anti-human tissue factor antibody targeting the factor X binding site.
Jiao JA, Kelly AB, Marzec UM, Nieves E, Acevedo J, Burkhardt M, Edwards A, Zhu XY, Chavaillaz PA, Wong A, Wong JL, Egan JO, Taylor D, Rhode PR, Wong HC. Jiao JA, et al. Among authors: wong a, wong hc, wong jl. Thromb Haemost. 2010 Jan;103(1):224-33. doi: 10.1160/TH09-06-0400. Epub 2009 Oct 26. Thromb Haemost. 2010. PMID: 20062929 Free PMC article.
361 results