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Sulforaphane and its methylcarbonyl analogs inhibit the LPS-stimulated inflammatory response in human monocytes through modulating cytokine production, suppressing chemotactic migration and phagocytosis in a NF-κB- and MAPK-dependent manner.
Reddy SA, Shelar SB, Dang TM, Lee BN, Yang H, Ong SM, Ng HL, Chui WK, Wong SC, Chew EH. Reddy SA, et al. Among authors: wong sc. Int Immunopharmacol. 2015 Feb;24(2):440-450. doi: 10.1016/j.intimp.2014.12.037. Epub 2015 Jan 10. Int Immunopharmacol. 2015. PMID: 25585231
Novel dual-targeting anti-proliferative dihydrotriazine-chalcone derivatives display suppression of cancer cell invasion and inflammation by inhibiting the NF-κB signaling pathway.
Gan FF, Zhang R, Ng HL, Karuppasamy M, Seah W, Yeap WH, Ong SM, Hadadi E, Wong SC, Chui WK, Chew EH. Gan FF, et al. Among authors: wong sc. Food Chem Toxicol. 2018 Jun;116(Pt B):238-248. doi: 10.1016/j.fct.2018.04.003. Epub 2018 Apr 7. Food Chem Toxicol. 2018. PMID: 29630947
1,075 results