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The erythromycin breath test reflects P-glycoprotein function independently of cytochrome P450 3A activity.
Kurnik D, Wood AJ, Wilkinson GR. Kurnik D, et al. Among authors: wood aj. Clin Pharmacol Ther. 2006 Sep;80(3):228-34. doi: 10.1016/j.clpt.2006.06.002. Clin Pharmacol Ther. 2006. PMID: 16952489 Clinical Trial.
Effect of the alpha2C-adrenoreceptor deletion322-325 variant on sympathetic activity and cardiovascular measures in healthy subjects.
Kurnik D, Muszkat M, Friedman EA, Sofowora GG, Diedrich A, Xie HG, Harris PA, Choi L, Wood AJ, Stein CM. Kurnik D, et al. Among authors: wood aj. J Hypertens. 2007 Apr;25(4):763-71. doi: 10.1097/HJH.0b013e328017f6e9. J Hypertens. 2007. PMID: 17351367
Alpha 1A-adrenergic receptor polymorphism and vascular response.
Sofowora GG, Dishy V, Landau R, Xie HG, Prasad HC, Byrne DW, Smiley RM, Kim RB, Wood AJ, Stein CM. Sofowora GG, et al. Among authors: wood aj. Clin Pharmacol Ther. 2004 Jun;75(6):539-45. doi: 10.1016/j.clpt.2004.02.006. Clin Pharmacol Ther. 2004. PMID: 15179408
CYP2A6 genetic variation and dexmedetomidine disposition.
Kohli U, Pandharipande P, Muszkat M, Sofowora GG, Friedman EA, Scheinin M, Wood AJ, Ely EW, Tyndale RF, Choi L, Stein CM, Kurnik D. Kohli U, et al. Among authors: wood aj. Eur J Clin Pharmacol. 2012 Jun;68(6):937-42. doi: 10.1007/s00228-011-1208-z. Epub 2012 Jan 21. Eur J Clin Pharmacol. 2012. PMID: 22271297 Free PMC article.
Tariquidar, a selective P-glycoprotein inhibitor, does not potentiate loperamide's opioid brain effects in humans despite full inhibition of lymphocyte P-glycoprotein.
Kurnik D, Sofowora GG, Donahue JP, Nair UB, Wilkinson GR, Wood AJ, Muszkat M. Kurnik D, et al. Among authors: wood aj. Anesthesiology. 2008 Dec;109(6):1092-9. doi: 10.1097/ALN.0b013e31818d8f28. Anesthesiology. 2008. PMID: 19034106 Clinical Trial.
Variation in the α(2A) adrenoceptor gene and the effect of dexmedetomidine on plasma insulin and glucose.
Ghimire LV, Muszkat M, Sofowora GG, Scheinin M, Wood AJ, Stein CM, Kurnik D. Ghimire LV, et al. Among authors: wood aj. Pharmacogenet Genomics. 2013 Sep;23(9):479-86. doi: 10.1097/FPC.0b013e3283642f93. Pharmacogenet Genomics. 2013. PMID: 23873118 Free PMC article. Clinical Trial.
Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine.
Kurnik D, Muszkat M, Li C, Sofowora GG, Friedman EA, Scheinin M, Wood AJ, Stein CM. Kurnik D, et al. Among authors: wood aj. Circ Cardiovasc Genet. 2011 Apr;4(2):179-87. doi: 10.1161/CIRCGENETICS.110.957662. Epub 2011 Feb 15. Circ Cardiovasc Genet. 2011. PMID: 21325151 Free PMC article. Clinical Trial.
Differential in vivo sensitivity to inhibition of P-glycoprotein located in lymphocytes, testes, and the blood-brain barrier.
Choo EF, Kurnik D, Muszkat M, Ohkubo T, Shay SD, Higginbotham JN, Glaeser H, Kim RB, Wood AJ, Wilkinson GR. Choo EF, et al. Among authors: wood aj. J Pharmacol Exp Ther. 2006 Jun;317(3):1012-8. doi: 10.1124/jpet.105.099648. Epub 2006 Mar 14. J Pharmacol Exp Ther. 2006. PMID: 16537797
Variations in the alpha2A-adrenergic receptor gene and their functional effects.
Kurnik D, Muszkat M, Li C, Sofowora GG, Solus J, Xie HG, Harris PA, Jiang L, McMunn C, Ihrie P, Dawson EP, Williams SM, Wood AJ, Stein CM. Kurnik D, et al. Among authors: wood aj. Clin Pharmacol Ther. 2006 Mar;79(3):173-85. doi: 10.1016/j.clpt.2005.10.006. Epub 2006 Feb 7. Clin Pharmacol Ther. 2006. PMID: 16513442
Effect of acute transdermal estrogen administration on basal, mental stress and cold pressor-induced sympathetic responses in postmenopausal women.
Sofowora GG, Singh I, He HB, Wood AJ, Stein CM. Sofowora GG, et al. Among authors: wood aj. Clin Auton Res. 2005 Jun;15(3):193-9. doi: 10.1007/s10286-005-0261-z. Clin Auton Res. 2005. PMID: 15944868
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