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Signalling role of adipose tissue: adipokines and inflammation in obesity.
Trayhurn P, Wood IS. Trayhurn P, et al. Among authors: wood is. Biochem Soc Trans. 2005 Nov;33(Pt 5):1078-81. doi: 10.1042/BST0331078. Biochem Soc Trans. 2005. PMID: 16246049 Review.
White adipose tissue (WAT) is a major endocrine and secretory organ, which releases a wide range of protein signals and factors termed adipokines. ...WAT is involved in extensive cross-talk with other organs and multiple metabolic systems through the various adipoki …
White adipose tissue (WAT) is a major endocrine and secretory organ, which releases a wide range of protein signals and factors terme …
PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes.
Wang B, Wood IS, Trayhurn P. Wang B, et al. Among authors: wood is. Biochem Biophys Res Commun. 2008 Mar 28;368(1):88-93. doi: 10.1016/j.bbrc.2008.01.036. Epub 2008 Jan 17. Biochem Biophys Res Commun. 2008. PMID: 18206644 Free PMC article.
MT-3 is a highly hypoxia-inducible gene in human adipocytes; the protein may protect adipocytes from hypoxic damage....
MT-3 is a highly hypoxia-inducible gene in human adipocytes; the protein may protect adipocytes from hypoxic damage....
Hypoxia induces leptin gene expression and secretion in human preadipocytes: differential effects of hypoxia on adipokine expression by preadipocytes.
Wang B, Wood IS, Trayhurn P. Wang B, et al. Among authors: wood is. J Endocrinol. 2008 Jul;198(1):127-34. doi: 10.1677/JOE-08-0156. Epub 2008 May 7. J Endocrinol. 2008. PMID: 18463145
It is concluded that hypoxia induces human preadipocytes to synthesize and secrete leptin. Preadipocytes and adipocytes differ in their responsiveness to low O(2) tension, maturation of the response to hypoxia developing on differentiation....
It is concluded that hypoxia induces human preadipocytes to synthesize and secrete leptin. Preadipocytes and adipocytes differ in the …
Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity?
Trayhurn P, Wang B, Wood IS. Trayhurn P, et al. Among authors: wood is. Br J Nutr. 2008 Aug;100(2):227-35. doi: 10.1017/S0007114508971282. Epub 2008 Apr 9. Br J Nutr. 2008. PMID: 18397542 Review.
White adipose tissue is a key endocrine and secretory organ, releasing multiple adipokines, many of which are linked to inflammation and immunity. ...We proposed in 2004 (Trayhurn & Wood, Br J Nutr 92, 347-355) that inflammation in adipose tissue in obesity i
White adipose tissue is a key endocrine and secretory organ, releasing multiple adipokines, many of which are linked to inflammation …
Hypoxia and the endocrine and signalling role of white adipose tissue.
Trayhurn P, Wang B, Wood IS. Trayhurn P, et al. Among authors: wood is. Arch Physiol Biochem. 2008 Oct;114(4):267-76. doi: 10.1080/13813450802306602. Arch Physiol Biochem. 2008. PMID: 18946787 Review.
Obesity, its associated disorders and the role of inflammatory adipokines in companion animals.
German AJ, Ryan VH, German AC, Wood IS, Trayhurn P. German AJ, et al. Among authors: wood is. Vet J. 2010 Jul;185(1):4-9. doi: 10.1016/j.tvjl.2010.04.004. Epub 2010 May 15. Vet J. 2010. PMID: 20472476 Review.
Adipokine expression and secretion by canine adipocytes: stimulation of inflammatory adipokine production by LPS and TNFalpha.
Ryan VH, German AJ, Wood IS, Hunter L, Morris P, Trayhurn P. Ryan VH, et al. Among authors: wood is. Pflugers Arch. 2010 Aug;460(3):603-16. doi: 10.1007/s00424-010-0845-x. Epub 2010 May 15. Pflugers Arch. 2010. PMID: 20473515
Modulation of adipokine production, glucose uptake and lactate release in human adipocytes by small changes in oxygen tension.
Wood IS, Stezhka T, Trayhurn P. Wood IS, et al. Pflugers Arch. 2011 Sep;462(3):469-77. doi: 10.1007/s00424-011-0985-7. Epub 2011 Jun 23. Pflugers Arch. 2011. PMID: 21698390
Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes.
Pérez de Heredia F, Wood IS, Trayhurn P. Pérez de Heredia F, et al. Among authors: wood is. Pflugers Arch. 2010 Feb;459(3):509-18. doi: 10.1007/s00424-009-0750-3. Epub 2009 Oct 30. Pflugers Arch. 2010. PMID: 19876643
Cellular hypoxia and adipose tissue dysfunction in obesity.
Wood IS, de Heredia FP, Wang B, Trayhurn P. Wood IS, et al. Proc Nutr Soc. 2009 Nov;68(4):370-7. doi: 10.1017/S0029665109990206. Epub 2009 Aug 24. Proc Nutr Soc. 2009. PMID: 19698203 Review.
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