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c-Jun is a negative regulator of myelination.
Parkinson DB, Bhaskaran A, Arthur-Farraj P, Noon LA, Woodhoo A, Lloyd AC, Feltri ML, Wrabetz L, Behrens A, Mirsky R, Jessen KR. Parkinson DB, et al. Among authors: woodhoo a. J Cell Biol. 2008 May 19;181(4):625-37. doi: 10.1083/jcb.200803013. J Cell Biol. 2008. PMID: 18490512 Free PMC article.
c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration.
Arthur-Farraj PJ, Latouche M, Wilton DK, Quintes S, Chabrol E, Banerjee A, Woodhoo A, Jenkins B, Rahman M, Turmaine M, Wicher GK, Mitter R, Greensmith L, Behrens A, Raivich G, Mirsky R, Jessen KR. Arthur-Farraj PJ, et al. Among authors: woodhoo a. Neuron. 2012 Aug 23;75(4):633-47. doi: 10.1016/j.neuron.2012.06.021. Neuron. 2012. PMID: 22920255 Free PMC article.
S-adenosylmethionine levels regulate the schwann cell DNA methylome.
Varela-Rey M, Iruarrizaga-Lejarreta M, Lozano JJ, Aransay AM, Fernandez AF, Lavin JL, Mósen-Ansorena D, Berdasco M, Turmaine M, Luka Z, Wagner C, Lu SC, Esteller M, Mirsky R, Jessen KR, Fraga MF, Martínez-Chantar ML, Mato JM, Woodhoo A. Varela-Rey M, et al. Among authors: woodhoo a. Neuron. 2014 Mar 5;81(5):1024-1039. doi: 10.1016/j.neuron.2014.01.037. Neuron. 2014. PMID: 24607226 Free PMC article.
Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves.
Gomez-Sanchez JA, Carty L, Iruarrizaga-Lejarreta M, Palomo-Irigoyen M, Varela-Rey M, Griffith M, Hantke J, Macias-Camara N, Azkargorta M, Aurrekoetxea I, De Juan VG, Jefferies HB, Aspichueta P, Elortza F, Aransay AM, Martínez-Chantar ML, Baas F, Mato JM, Mirsky R, Woodhoo A, Jessen KR. Gomez-Sanchez JA, et al. Among authors: woodhoo a. J Cell Biol. 2015 Jul 6;210(1):153-68. doi: 10.1083/jcb.201503019. J Cell Biol. 2015. PMID: 26150392 Free PMC article.
HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis.
Palomo-Irigoyen M, Pérez-Andrés E, Iruarrizaga-Lejarreta M, Barreira-Manrique A, Tamayo-Caro M, Vila-Vecilla L, Moreno-Cugnon L, Beitia N, Medrano D, Fernández-Ramos D, Lozano JJ, Okawa S, Lavín JL, Martín-Martín N, Sutherland JD, de Juan VG, Gonzalez-Lopez M, Macías-Cámara N, Mosén-Ansorena D, Laraba L, Hanemann CO, Ercolano E, Parkinson DB, Schultz CW, Araúzo-Bravo MJ, Ascensión AM, Gerovska D, Iribar H, Izeta A, Pytel P, Krastel P, Provenzani A, Seneci P, Carrasco RD, Del Sol A, Martinez-Chantar ML, Barrio R, Serra E, Lazaro C, Flanagan AM, Gorospe M, Ratner N, Aransay AM, Carracedo A, Varela-Rey M, Woodhoo A. Palomo-Irigoyen M, et al. Among authors: woodhoo a. J Clin Invest. 2020 Jul 1;130(7):3848-3864. doi: 10.1172/JCI130379. J Clin Invest. 2020. PMID: 32315290 Free PMC article.
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