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Plasmin activity in the porcine airways is enhanced during experimental infection with Mycoplasma hyopneumoniae, is positively correlated with proinflammatory cytokine levels and is ameliorated by vaccination.
Woolley LK, Fell SA, Djordjevic SP, Eamens GJ, Jenkins C. Woolley LK, et al. Vet Microbiol. 2013 May 31;164(1-2):60-6. doi: 10.1016/j.vetmic.2013.02.003. Epub 2013 Feb 14. Vet Microbiol. 2013. PMID: 23490555
MHJ_0125 is an M42 glutamyl aminopeptidase that moonlights as a multifunctional adhesin on the surface of Mycoplasma hyopneumoniae.
Robinson MW, Buchtmann KA, Jenkins C, Tacchi JL, Raymond BB, To J, Roy Chowdhury P, Woolley LK, Labbate M, Turnbull L, Whitchurch CB, Padula MP, Djordjevic SP. Robinson MW, et al. Among authors: woolley lk. Open Biol. 2013 Apr 17;3(4):130017. doi: 10.1098/rsob.130017. Open Biol. 2013. PMID: 23594879 Free PMC article.
Evaluation of recombinant Mycoplasma hyopneumoniae P97/P102 paralogs formulated with selected adjuvants as vaccines against mycoplasmal pneumonia in pigs.
Woolley LK, Fell SA, Gonsalves JR, Raymond BB, Collins D, Kuit TA, Walker MJ, Djordjevic SP, Eamens GJ, Jenkins C. Woolley LK, et al. Vaccine. 2014 Jul 23;32(34):4333-41. doi: 10.1016/j.vaccine.2014.06.008. Epub 2014 Jun 12. Vaccine. 2014. PMID: 24930717
Post-translational processing targets functionally diverse proteins in Mycoplasma hyopneumoniae.
Tacchi JL, Raymond BB, Haynes PA, Berry IJ, Widjaja M, Bogema DR, Woolley LK, Jenkins C, Minion FC, Padula MP, Djordjevic SP. Tacchi JL, et al. Among authors: woolley lk. Open Biol. 2016 Feb;6(2):150210. doi: 10.1098/rsob.150210. Open Biol. 2016. PMID: 26865024 Free PMC article.
Evaluation of clinical, histological and immunological changes and qPCR detection of Mycoplasma hyopneumoniae in tissues during the early stages of mycoplasmal pneumonia in pigs after experimental challenge with two field isolates.
Woolley LK, Fell S, Gonsalves JR, Walker MJ, Djordjevic SP, Jenkins C, Eamens GJ. Woolley LK, et al. Vet Microbiol. 2012 Dec 28;161(1-2):186-95. doi: 10.1016/j.vetmic.2012.07.025. Epub 2012 Jul 22. Vet Microbiol. 2012. PMID: 22863144
Mhp182 (P102) binds fibronectin and contributes to the recruitment of plasmin(ogen) to the Mycoplasma hyopneumoniae cell surface.
Seymour LM, Jenkins C, Deutscher AT, Raymond BB, Padula MP, Tacchi JL, Bogema DR, Eamens GJ, Woolley LK, Dixon NE, Walker MJ, Djordjevic SP. Seymour LM, et al. Among authors: woolley lk. Cell Microbiol. 2012 Jan;14(1):81-94. doi: 10.1111/j.1462-5822.2011.01702.x. Epub 2011 Nov 9. Cell Microbiol. 2012. PMID: 21951786
Characterization of cleavage events in the multifunctional cilium adhesin Mhp684 (P146) reveals a mechanism by which Mycoplasma hyopneumoniae regulates surface topography.
Bogema DR, Deutscher AT, Woolley LK, Seymour LM, Raymond BB, Tacchi JL, Padula MP, Dixon NE, Minion FC, Jenkins C, Walker MJ, Djordjevic SP. Bogema DR, et al. Among authors: woolley lk. mBio. 2012 Apr 3;3(2):e00282-11. doi: 10.1128/mBio.00282-11. Print 2012. mBio. 2012. PMID: 22493032 Free PMC article.
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