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Page 1
Did you mean bookman cj[Author] (1 results)?
Regulatory T cells in the tumour microenvironment.
Imianowski CJ, Chen Q, Workman CJ, Vignali DAA. Imianowski CJ, et al. Among authors: workman cj. Nat Rev Cancer. 2025 Sep;25(9):703-722. doi: 10.1038/s41568-025-00832-9. Epub 2025 Jun 10. Nat Rev Cancer. 2025. PMID: 40494998 Review.
Multiplex targeting of immune-modulating genes in cancer.
Braverman EL, Vignali DAA, Workman CJ. Braverman EL, et al. Among authors: workman cj. Nat Immunol. 2025 Apr;26(4):531-533. doi: 10.1038/s41590-025-02115-9. Nat Immunol. 2025. PMID: 40108420 No abstract available.
Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs.
Jiang Y, Dai A, Huang Y, Li H, Cui J, Yang H, Si L, Jiao T, Ren Z, Zhang Z, Mou S, Zhu H, Guo W, Huang Q, Li Y, Xue M, Jiang J, Wang F, Li L, Zhong Q, Wang K, Liu B, Wang J, Fan G, Guo J, Chen L, Workman CJ, Shen Z, Kong Y, Vignali DAA, Xu C, Wang H. Jiang Y, et al. Among authors: workman cj. Cell. 2025 May 1;188(9):2354-2371.e18. doi: 10.1016/j.cell.2025.02.014. Epub 2025 Mar 17. Cell. 2025. PMID: 40101708 Free article.
Neuronal LAG3 facilitates pathogenic α-synuclein neuron-to-neuron propagation.
Yang X, Jeong D, Madeo G, Kumbhar R, Wang N, Niu L, Hu J, Li S, Gadhave K, Chen R, Akkentli F, Workman CJ, Vignali DAA, Ying M, Bonci A, Dawson VL, Dawson TM, Mao X. Yang X, et al. Among authors: workman cj. bioRxiv [Preprint]. 2025 Jan 3:2025.01.03.631221. doi: 10.1101/2025.01.03.631221. bioRxiv. 2025. PMID: 39803449 Free PMC article. Preprint.
Advances in LAG3 cancer immunotherapeutics.
Adam K, Butler SC, Workman CJ, Vignali DAA. Adam K, et al. Among authors: workman cj. Trends Cancer. 2025 Jan;11(1):37-48. doi: 10.1016/j.trecan.2024.10.009. Epub 2024 Nov 26. Trends Cancer. 2025. PMID: 39603977 Free PMC article. Review.
Ebi3 Binding to IFN-γ and IL-10 Limits Their Function.
Scott EN, Ye C, Yano H, Lipatova Z, Brunazzi E, Vignali KM, Workman CJ, Vignali DAA. Scott EN, et al. Among authors: workman cj. J Immunol. 2024 Oct 15;213(8):1115-1124. doi: 10.4049/jimmunol.2400236. J Immunol. 2024. PMID: 39240167 Free PMC article.
Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity.
Cillo AR, Cardello C, Shan F, Karapetyan L, Kunning S, Sander C, Rush E, Karunamurthy A, Massa RC, Rohatgi A, Workman CJ, Kirkwood JM, Bruno TC, Vignali DAA. Cillo AR, et al. Among authors: workman cj. Cell. 2024 Aug 8;187(16):4373-4388.e15. doi: 10.1016/j.cell.2024.06.036. Cell. 2024. PMID: 39121849 Free PMC article. Clinical Trial.
LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity.
Andrews LP, Butler SC, Cui J, Cillo AR, Cardello C, Liu C, Brunazzi EA, Baessler A, Xie B, Kunning SR, Ngiow SF, Huang YJ, Manne S, Sharpe AH, Delgoffe GM, Wherry EJ, Kirkwood JM, Bruno TC, Workman CJ, Vignali DAA. Andrews LP, et al. Among authors: workman cj. Cell. 2024 Aug 8;187(16):4355-4372.e22. doi: 10.1016/j.cell.2024.07.016. Cell. 2024. PMID: 39121848 Free PMC article.
91 results