Workman P - Search Results

1

A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.

Rayter S, Elliott R, Travers J, Rowlands MG, Richardson TB, Boxall K, Jones K, Linardopoulos S, Workman P, Aherne W, Lord CJ, Ashworth A. Rayter S, et al. Among authors: workman p. Oncogene. 2008 Feb 14;27(8):1036-44. doi: 10.1038/sj.onc.1210729. Epub 2007 Aug 13. Oncogene. 2008. PMID: 17700519

2

Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone.

Clarke PA, Hostein I, Banerji U, Stefano FD, Maloney A, Walton M, Judson I, Workman P. Clarke PA, et al. Among authors: workman p. Oncogene. 2000 Aug 24;19(36):4125-33. doi: 10.1038/sj.onc.1203753. Oncogene. 2000. PMID: 10962573

3

High-throughput screening for identification of small molecule inhibitors of histone acetyltransferases using scintillating microplates (FlashPlate).

Turlais F, Hardcastle A, Rowlands M, Newbatt Y, Bannister A, Kouzarides T, Workman P, Aherne GW. Turlais F, et al. Among authors: workman p. Anal Biochem. 2001 Nov 1;298(1):62-8. doi: 10.1006/abio.2001.5340. Anal Biochem. 2001. PMID: 11673896

4

Assays for the identification and evaluation of histone acetyltransferase inhibitors.

Wynne Aherne G, Rowlands MG, Stimson L, Workman P. Wynne Aherne G, et al. Among authors: workman p. Methods. 2002 Mar;26(3):245-53. doi: 10.1016/S1046-2023(02)00028-2. Methods. 2002. PMID: 12054880

5

Establishment and characterization of acquired resistance to the farnesyl protein transferase inhibitor R115777 in a human colon cancer cell line.

Smith V, Rowlands MG, Barrie E, Workman P, Kelland LR. Smith V, et al. Among authors: workman p. Clin Cancer Res. 2002 Jun;8(6):2002-9. Clin Cancer Res. 2002. PMID: 12060646

6

Assays for HSP90 and inhibitors.

Aherne W, Maloney A, Prodromou C, Rowlands MG, Hardcastle A, Boxall K, Clarke P, Walton MI, Pearl L, Workman P. Aherne W, et al. Among authors: workman p. Methods Mol Med. 2003;85:149-61. doi: 10.1385/1-59259-380-1:149. Methods Mol Med. 2003. PMID: 12710206 Review. No abstract available.

7

High-throughput screening for the identification of small-molecule inhibitors of retinoblastoma protein phosphorylation in cells.

Barrie SE, Eno-Amooquaye E, Hardcastle A, Platt G, Richards J, Bedford D, Workman P, Aherne W, Mittnacht S, Garrett MD. Barrie SE, et al. Among authors: workman p. Anal Biochem. 2003 Sep 1;320(1):66-74. doi: 10.1016/s0003-2697(03)00349-x. Anal Biochem. 2003. PMID: 12895470

8

High-throughput screening assay for inhibitors of heat-shock protein 90 ATPase activity.

Rowlands MG, Newbatt YM, Prodromou C, Pearl LH, Workman P, Aherne W. Rowlands MG, et al. Among authors: workman p. Anal Biochem. 2004 Apr 15;327(2):176-83. doi: 10.1016/j.ab.2003.10.038. Anal Biochem. 2004. PMID: 15051534

9

Histone modification enzymes: novel targets for cancer drugs.

Kristeleit R, Stimson L, Workman P, Aherne W. Kristeleit R, et al. Among authors: workman p. Expert Opin Emerg Drugs. 2004 May;9(1):135-54. doi: 10.1517/eoed.9.1.135.32947. Expert Opin Emerg Drugs. 2004. PMID: 15155140 Review.

10

Structure-activity relationships in purine-based inhibitor binding to HSP90 isoforms.

Wright L, Barril X, Dymock B, Sheridan L, Surgenor A, Beswick M, Drysdale M, Collier A, Massey A, Davies N, Fink A, Fromont C, Aherne W, Boxall K, Sharp S, Workman P, Hubbard RE. Wright L, et al. Among authors: workman p. Chem Biol. 2004 Jun;11(6):775-85. doi: 10.1016/j.chembiol.2004.03.033. Chem Biol. 2004. PMID: 15217611

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

603 results

Search Page