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Origins and functions of B-1 cells with notes on the role of CD5.
Berland R, Wortis HH. Berland R, et al. Among authors: wortis hh. Annu Rev Immunol. 2002;20:253-300. doi: 10.1146/annurev.immunol.20.100301.064833. Epub 2001 Oct 4. Annu Rev Immunol. 2002. PMID: 11861604 Review.
To B-1 or not to B-1.
Wortis HH. Wortis HH. Nat Immunol. 2017 Mar 22;18(4):365-366. doi: 10.1038/ni.3715. Nat Immunol. 2017. PMID: 28323267 No abstract available.
Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice.
Berland R, Fernandez L, Kari E, Han JH, Lomakin I, Akira S, Wortis HH, Kearney JF, Ucci AA, Imanishi-Kari T. Berland R, et al. Among authors: wortis hh. Immunity. 2006 Sep;25(3):429-40. doi: 10.1016/j.immuni.2006.07.014. Immunity. 2006. PMID: 16973388 Free article.
CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity.
Chen J, McLean PA, Neel BG, Okunade G, Shull GE, Wortis HH. Chen J, et al. Among authors: wortis hh. Nat Immunol. 2004 Jun;5(6):651-7. doi: 10.1038/ni1072. Epub 2004 May 9. Nat Immunol. 2004. PMID: 15133509
Normal B-1a cell development requires B cell-intrinsic NFATc1 activity.
Berland R, Wortis HH. Berland R, et al. Among authors: wortis hh. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13459-64. doi: 10.1073/pnas.2233620100. Epub 2003 Oct 31. Proc Natl Acad Sci U S A. 2003. PMID: 14595020 Free PMC article.
Sialic acid binding domains of CD22 are required for negative regulation of B cell receptor signaling.
Jin L, McLean PA, Neel BG, Wortis HH. Jin L, et al. Among authors: wortis hh. J Exp Med. 2002 May 6;195(9):1199-205. doi: 10.1084/jem.20011796. J Exp Med. 2002. PMID: 11994425 Free PMC article.
The Trypanosoma cruzi trans-sialidase is a T cell-independent B cell mitogen and an inducer of non-specific Ig secretion.
Gao W, Wortis HH, Pereira MA. Gao W, et al. Among authors: wortis hh. Int Immunol. 2002 Mar;14(3):299-308. doi: 10.1093/intimm/14.3.299. Int Immunol. 2002. PMID: 11867566
A conserved enhancer element differentially regulates developmental expression of CD5 in B and T cells.
Berland R, Fiering S, Wortis HH. Berland R, et al. Among authors: wortis hh. J Immunol. 2010 Dec 15;185(12):7537-43. doi: 10.4049/jimmunol.1002173. Epub 2010 Nov 12. J Immunol. 2010. PMID: 21076064 Free PMC article.
Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation.
Bajpai UD, Zhang K, Teutsch M, Sen R, Wortis HH. Bajpai UD, et al. Among authors: wortis hh. J Exp Med. 2000 May 15;191(10):1735-44. doi: 10.1084/jem.191.10.1735. J Exp Med. 2000. PMID: 10811866 Free PMC article.
B cell antigen receptor-evoked calcium influx is enhanced in CD22-deficient B cell lines.
Nadler MJ, McLean PA, Neel BG, Wortis HH. Nadler MJ, et al. Among authors: wortis hh. J Immunol. 1997 Nov 1;159(9):4233-43. J Immunol. 1997. PMID: 9379018
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