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Bisperoxovanadium compounds are potent PTEN inhibitors.
Schmid AC, Byrne RD, Vilar R, Woscholski R. Schmid AC, et al. Among authors: woscholski r. FEBS Lett. 2004 May 21;566(1-3):35-8. doi: 10.1016/j.febslet.2004.03.102. FEBS Lett. 2004. PMID: 15147864
A unified nomenclature and amino acid numbering for human PTEN.
Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, Jiang X, Lee SR, Lösche M, Malaney P, Matias-Guiu X, Molina M, Pandolfi PP, Parsons R, Pinton P, Rivas C, Rocha RM, Rodríguez MS, Ross AH, Serrano M, Stambolic V, Stiles B, Suzuki A, Tan SS, Tonks NK, Trotman LC, Wolff N, Woscholski R, Wu H, Leslie NR. Pulido R, et al. Among authors: woscholski r. Sci Signal. 2014 Jul 1;7(332):pe15. doi: 10.1126/scisignal.2005560. Sci Signal. 2014. PMID: 24985344 Free PMC article.
Vanadyl complexes with dansyl-labelled di-picolinic acid ligands: synthesis, phosphatase inhibition activity and cellular uptake studies.
Collins J, Cilibrizzi A, Fedorova M, Whyte G, Mak LH, Guterman I, Leatherbarrow R, Woscholski R, Vilar R. Collins J, et al. Among authors: woscholski r. Dalton Trans. 2016 Apr 28;45(16):7104-13. doi: 10.1039/c5dt04753f. Epub 2016 Mar 23. Dalton Trans. 2016. PMID: 27008377 Free article.
Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins.
Verrastro I, Tveen-Jensen K, Woscholski R, Spickett CM, Pitt AR. Verrastro I, et al. Among authors: woscholski r. Free Radic Biol Med. 2016 Jan;90:24-34. doi: 10.1016/j.freeradbiomed.2015.11.004. Epub 2015 Nov 10. Free Radic Biol Med. 2016. PMID: 26561776 Free article.
A tri-functional vanadium(iv) complex to detect cysteine oxidation.
Cilibrizzi A, Fedorova M, Collins J, Leatherbarrow R, Woscholski R, Vilar R. Cilibrizzi A, et al. Among authors: woscholski r. Dalton Trans. 2017 May 30;46(21):6994-7004. doi: 10.1039/c7dt00076f. Dalton Trans. 2017. PMID: 28513686 Free article.
Removal or masking of phosphatidylinositol(4,5)bisphosphate from the outer mitochondrial membrane causes mitochondrial fragmentation.
Rosivatz E, Woscholski R. Rosivatz E, et al. Among authors: woscholski r. Cell Signal. 2011 Feb;23(2):478-86. doi: 10.1016/j.cellsig.2010.10.025. Epub 2010 Oct 30. Cell Signal. 2011. PMID: 21044681 Free PMC article.
Type II phosphoinositide 5-phosphatases have unique sensitivities towards fatty acid composition and head group phosphorylation.
Schmid AC, Wise HM, Mitchell CA, Nussbaum R, Woscholski R. Schmid AC, et al. Among authors: woscholski r. FEBS Lett. 2004 Oct 8;576(1-2):9-13. doi: 10.1016/j.febslet.2004.08.052. FEBS Lett. 2004. PMID: 15474001
Characterization and purification of phosphatidylinositol trisphosphate 5-phosphatase from rat brain tissues.
Woscholski R. Woscholski R. Methods Enzymol. 2002;345:335-45. doi: 10.1016/s0076-6879(02)45027-6. Methods Enzymol. 2002. PMID: 11665617 No abstract available.
A small molecule mimicking a phosphatidylinositol (4,5)-bisphosphate binding pleckstrin homology domain.
Mak LH, Georgiades SN, Rosivatz E, Whyte GF, Mirabelli M, Vilar R, Woscholski R. Mak LH, et al. Among authors: woscholski r. ACS Chem Biol. 2011 Dec 16;6(12):1382-90. doi: 10.1021/cb2003187. Epub 2011 Oct 10. ACS Chem Biol. 2011. PMID: 21958214
A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN).
Rosivatz E, Matthews JG, McDonald NQ, Mulet X, Ho KK, Lossi N, Schmid AC, Mirabelli M, Pomeranz KM, Erneux C, Lam EW, Vilar R, Woscholski R. Rosivatz E, et al. Among authors: woscholski r. ACS Chem Biol. 2006 Dec 15;1(12):780-90. doi: 10.1021/cb600352f. ACS Chem Biol. 2006. PMID: 17240976
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