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mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 Omicron variant.
Edara VV, Manning KE, Ellis M, Lai L, Moore KM, Foster SL, Floyd K, Davis-Gardner ME, Mantus G, Nyhoff LE, Bechnak S, Alaaeddine G, Naji A, Samaha H, Lee M, Bristow L, Hussaini L, Ciric CR, Nguyen PV, Gagne M, Roberts-Torres J, Henry AR, Godbole S, Grakoui A, Sexton M, Piantadosi A, Waggoner JJ, Douek DC, Anderson EJ, Rouphael N, Wrammert J, Suthar MS. Edara VV, et al. Among authors: wrammert j. bioRxiv [Preprint]. 2021 Dec 22:2021.12.20.473557. doi: 10.1101/2021.12.20.473557. bioRxiv. 2021. PMID: 34981056 Free PMC article. Updated. Preprint.
Epistasis reduces fitness costs of influenza A virus escape from stem-binding antibodies.
Lee CY, Raghunathan V, Caceres CJ, Geiger G, Seibert B, Cargnin Faccin F, Gay LC, Ferreri LM, Kaul D, Wrammert J, Tan GS, Perez DR, Lowen AC. Lee CY, et al. Among authors: wrammert j. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2208718120. doi: 10.1073/pnas.2208718120. Epub 2023 Apr 17. Proc Natl Acad Sci U S A. 2023. PMID: 37068231 Free PMC article.
An inactivated NDV-HXP-S COVID-19 vaccine elicits a higher proportion of neutralizing antibodies in humans than mRNA vaccination.
Carreño JM, Raskin A, Singh G, Tcheou J, Kawabata H, Gleason C, Srivastava K, Vigdorovich V, Dambrauskas N, Gupta SL, González Domínguez I, Martinez JL, Slamanig S, Sather DN, Raghunandan R, Wirachwong P, Muangnoicharoen S, Pitisuttithum P, Wrammert J, Suthar MS, Sun W, Palese P, García-Sastre A, Simon V, Krammer F. Carreño JM, et al. Among authors: wrammert j. Sci Transl Med. 2023 Feb 15;15(683):eabo2847. doi: 10.1126/scitranslmed.abo2847. Epub 2023 Feb 15. Sci Transl Med. 2023. PMID: 36791207 Free article.
Rapid cloning of high-affinity human monoclonal antibodies against influenza virus.
Wrammert J, Smith K, Miller J, Langley WA, Kokko K, Larsen C, Zheng NY, Mays I, Garman L, Helms C, James J, Air GM, Capra JD, Ahmed R, Wilson PC. Wrammert J, et al. Nature. 2008 May 29;453(7195):667-71. doi: 10.1038/nature06890. Epub 2008 Apr 30. Nature. 2008. PMID: 18449194 Free PMC article. Clinical Trial.
Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies.
Doria-Rose NA, Klein RM, Manion MM, O'Dell S, Phogat A, Chakrabarti B, Hallahan CW, Migueles SA, Wrammert J, Ahmed R, Nason M, Wyatt RT, Mascola JR, Connors M. Doria-Rose NA, et al. Among authors: wrammert j. J Virol. 2009 Jan;83(1):188-99. doi: 10.1128/JVI.01583-08. Epub 2008 Oct 15. J Virol. 2009. PMID: 18922865 Free PMC article.
Maintenance of serological memory.
Wrammert J, Ahmed R. Wrammert J, et al. Biol Chem. 2008 May;389(5):537-9. doi: 10.1515/bc.2008.066. Biol Chem. 2008. PMID: 18953719 Review.
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection.
Wrammert J, Koutsonanos D, Li GM, Edupuganti S, Sui J, Morrissey M, McCausland M, Skountzou I, Hornig M, Lipkin WI, Mehta A, Razavi B, Del Rio C, Zheng NY, Lee JH, Huang M, Ali Z, Kaur K, Andrews S, Amara RR, Wang Y, Das SR, O'Donnell CD, Yewdell JW, Subbarao K, Marasco WA, Mulligan MJ, Compans R, Ahmed R, Wilson PC. Wrammert J, et al. J Exp Med. 2011 Jan 17;208(1):181-93. doi: 10.1084/jem.20101352. Epub 2011 Jan 10. J Exp Med. 2011. PMID: 21220454 Free PMC article.
Systems biology of vaccination for seasonal influenza in humans.
Nakaya HI, Wrammert J, Lee EK, Racioppi L, Marie-Kunze S, Haining WN, Means AR, Kasturi SP, Khan N, Li GM, McCausland M, Kanchan V, Kokko KE, Li S, Elbein R, Mehta AK, Aderem A, Subbarao K, Ahmed R, Pulendran B. Nakaya HI, et al. Among authors: wrammert j. Nat Immunol. 2011 Jul 10;12(8):786-95. doi: 10.1038/ni.2067. Nat Immunol. 2011. PMID: 21743478 Free PMC article.
143 results