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A Phylogenetic and Phenotypic Analysis of Salmonella enterica Serovar Weltevreden, an Emerging Agent of Diarrheal Disease in Tropical Regions.
Makendi C, Page AJ, Wren BW, Le Thi Phuong T, Clare S, Hale C, Goulding D, Klemm EJ, Pickard D, Okoro C, Hunt M, Thompson CN, Phu Huong Lan N, Tran Do Hoang N, Thwaites GE, Le Hello S, Brisabois A, Weill FX, Baker S, Dougan G. Makendi C, et al. Among authors: wren bw. PLoS Negl Trop Dis. 2016 Feb 11;10(2):e0004446. doi: 10.1371/journal.pntd.0004446. eCollection 2016 Feb. PLoS Negl Trop Dis. 2016. PMID: 26867150 Free PMC article.
The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome.
Sebaihia M, Wren BW, Mullany P, Fairweather NF, Minton N, Stabler R, Thomson NR, Roberts AP, Cerdeño-Tárraga AM, Wang H, Holden MT, Wright A, Churcher C, Quail MA, Baker S, Bason N, Brooks K, Chillingworth T, Cronin A, Davis P, Dowd L, Fraser A, Feltwell T, Hance Z, Holroyd S, Jagels K, Moule S, Mungall K, Price C, Rabbinowitsch E, Sharp S, Simmonds M, Stevens K, Unwin L, Whithead S, Dupuy B, Dougan G, Barrell B, Parkhill J. Sebaihia M, et al. Among authors: wren bw. Nat Genet. 2006 Jul;38(7):779-86. doi: 10.1038/ng1830. Epub 2006 Jun 25. Nat Genet. 2006. PMID: 16804543
The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081.
Thomson NR, Howard S, Wren BW, Holden MT, Crossman L, Challis GL, Churcher C, Mungall K, Brooks K, Chillingworth T, Feltwell T, Abdellah Z, Hauser H, Jagels K, Maddison M, Moule S, Sanders M, Whitehead S, Quail MA, Dougan G, Parkhill J, Prentice MB. Thomson NR, et al. Among authors: wren bw. PLoS Genet. 2006 Dec 15;2(12):e206. doi: 10.1371/journal.pgen.0020206. PLoS Genet. 2006. PMID: 17173484 Free PMC article.
Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts.
Lawley TD, Clare S, Walker AW, Goulding D, Stabler RA, Croucher N, Mastroeni P, Scott P, Raisen C, Mottram L, Fairweather NF, Wren BW, Parkhill J, Dougan G. Lawley TD, et al. Among authors: wren bw. Infect Immun. 2009 Sep;77(9):3661-9. doi: 10.1128/IAI.00558-09. Epub 2009 Jun 29. Infect Immun. 2009. PMID: 19564382 Free PMC article.
Evolutionary dynamics of Clostridium difficile over short and long time scales.
He M, Sebaihia M, Lawley TD, Stabler RA, Dawson LF, Martin MJ, Holt KE, Seth-Smith HM, Quail MA, Rance R, Brooks K, Churcher C, Harris D, Bentley SD, Burrows C, Clark L, Corton C, Murray V, Rose G, Thurston S, van Tonder A, Walker D, Wren BW, Dougan G, Parkhill J. He M, et al. Among authors: wren bw. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7527-32. doi: 10.1073/pnas.0914322107. Epub 2010 Apr 5. Proc Natl Acad Sci U S A. 2010. PMID: 20368420 Free PMC article.
The Clostridium difficile spo0A gene is a persistence and transmission factor.
Deakin LJ, Clare S, Fagan RP, Dawson LF, Pickard DJ, West MR, Wren BW, Fairweather NF, Dougan G, Lawley TD. Deakin LJ, et al. Among authors: wren bw. Infect Immun. 2012 Aug;80(8):2704-11. doi: 10.1128/IAI.00147-12. Epub 2012 May 21. Infect Immun. 2012. PMID: 22615253 Free PMC article.
Emergence and global spread of epidemic healthcare-associated Clostridium difficile.
He M, Miyajima F, Roberts P, Ellison L, Pickard DJ, Martin MJ, Connor TR, Harris SR, Fairley D, Bamford KB, D'Arc S, Brazier J, Brown D, Coia JE, Douce G, Gerding D, Kim HJ, Koh TH, Kato H, Senoh M, Louie T, Michell S, Butt E, Peacock SJ, Brown NM, Riley T, Songer G, Wilcox M, Pirmohamed M, Kuijper E, Hawkey P, Wren BW, Dougan G, Parkhill J, Lawley TD. He M, et al. Among authors: wren bw. Nat Genet. 2013 Jan;45(1):109-13. doi: 10.1038/ng.2478. Epub 2012 Dec 9. Nat Genet. 2013. PMID: 23222960 Free PMC article.
335 results