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Enhancement of bacterial gene expression by insertion elements or by mutation in a CAP-cAMP binding site.
Reynolds AE, Mahadevan S, LeGrice SF, Wright A. Reynolds AE, et al. Among authors: wright a. J Mol Biol. 1986 Sep 5;191(1):85-95. doi: 10.1016/0022-2836(86)90424-9. J Mol Biol. 1986. PMID: 3025456
The ethylmethane sulfonate-induced point mutations in bglR are alterations in a single base in the cAMP binding protein (CAP) binding site, leading to a stronger binding of the CAP-cAMP complex. ...
The ethylmethane sulfonate-induced point mutations in bglR are alterations in a single base in the cAMP binding protein (CAP) binding …
DNA methylation differentially enhances the expression of one of the two E. coli dnaA promoters in vivo and in vitro.
Braun RE, Wright A. Braun RE, et al. Among authors: wright a. Mol Gen Genet. 1986 Feb;202(2):246-50. doi: 10.1007/BF00331644. Mol Gen Genet. 1986. PMID: 3010047
The decrease in the expression of dnaA was measured in vivo using a dnaA-lacZ gene fusion. In vivo S1 nuclease mapping demonstrated that the decrease was due to a differential decrease in expression from the more proximal of the two dnaA promoters, dnaA2P. ...
The decrease in the expression of dnaA was measured in vivo using a dnaA-lacZ gene fusion. In vivo S1 nuclease mapping demonstrated t …
A bacterial gene involved in transcription antitermination: regulation at a rho-independent terminator in the bgl operon of E. coli.
Mahadevan S, Wright A. Mahadevan S, et al. Among authors: wright a. Cell. 1987 Jul 31;50(3):485-94. doi: 10.1016/0092-8674(87)90502-2. Cell. 1987. PMID: 3301003
A regulatory region has been located downstream of the bgl promoter, revealing a 130 base leader containing a sequence from +64 to +112 characteristic of a rho-independent terminator. ...A mutation resulting in partially constitutive expression
A regulatory region has been located downstream of the bgl promoter, revealing a 130 base leader containing a sequence
Autoregulation of the DNA replication gene dnaA in E. coli K-12.
Braun RE, O'Day K, Wright A. Braun RE, et al. Among authors: wright a. Cell. 1985 Jan;40(1):159-69. doi: 10.1016/0092-8674(85)90319-8. Cell. 1985. PMID: 2981626
In this paper we report that the expression of both a dnaA-lacZ translational fusion and a dnaA-trpA-lacZ transcriptional fusion in vivo are sensitive to changes in the level of functional dnaA protein. ...Results from a deletion analysis of the dnaA promoter …
In this paper we report that the expression of both a dnaA-lacZ translational fusion and a dnaA-trpA-lacZ transcriptional fusi …
Multiple effects of an RNA polymerase beta' mutation on in vitro transcription.
Young BS, Wright A. Young BS, et al. Among authors: wright a. Mol Gen Genet. 1977 Oct 20;155(2):191-6. doi: 10.1007/BF00393159. Mol Gen Genet. 1977. PMID: 337127
S. tyrphimurium strain BY324 is temperature sensitive due to a mutation (rpo C32) in the gene for the RNA polymerase beta' subunit. ...
S. tyrphimurium strain BY324 is temperature sensitive due to a mutation (rpo C32) in the gene for the RNA polymerase beta' subunit. . …
Plasmid pSC101 replication in integratively suppressed cells requires dnaA function.
Felton J, Wright A. Felton J, et al. Among authors: wright a. Mol Gen Genet. 1979 Sep;175(2):231-3. doi: 10.1007/BF00425541. Mol Gen Genet. 1979. PMID: 390317
Maintenance of plasmid pKC17, a derivative of plasmid pSC101, in E. coli requires a functional dnaA gene product. This was demonstrated by segregation experiments using an E. coli dnaA46 mutant, at various temperatures. Growth of this mutant at elevated temperature …
Maintenance of plasmid pKC17, a derivative of plasmid pSC101, in E. coli requires a functional dnaA gene product. This was dem …
Isolation and characterization of amber mutations in gene dnaA of escherichia coli K-12.
Schaus N, O'Day K, Peters W, Wright A. Schaus N, et al. Among authors: wright a. J Bacteriol. 1981 Feb;145(2):904-13. doi: 10.1128/JB.145.2.904-913.1981. J Bacteriol. 1981. PMID: 7007354 Free PMC article.
We isolated 36 mutants defective in the initiation of deoxyribonucleic acid replication as determined by their dependence upon integrative suppression by a P2 sig5 prophage. Three of the 36 mutants were shown to contain amber mutations through the use of a temperatu …
We isolated 36 mutants defective in the initiation of deoxyribonucleic acid replication as determined by their dependence upon integrative s …
Escherichia coli DNA topoisomerase I mutants have compensatory mutations at or near DNA gyrase genes.
DiNardo S, Voelkel KA, Sternglanz R, Reynolds AE, Wright A. DiNardo S, et al. Among authors: wright a. Cold Spring Harb Symp Quant Biol. 1983;47 Pt 2:779-84. doi: 10.1101/sqb.1983.047.01.089. Cold Spring Harb Symp Quant Biol. 1983. PMID: 6305586 No abstract available.
Escherichia coli DNA topoisomerase I mutants have compensatory mutations in DNA gyrase genes.
DiNardo S, Voelkel KA, Sternglanz R, Reynolds AE, Wright A. DiNardo S, et al. Among authors: wright a. Cell. 1982 Nov;31(1):43-51. doi: 10.1016/0092-8674(82)90403-2. Cell. 1982. PMID: 6297752
Escherichia coli deletion mutants lacking DNA topoisomerase I have been identified previously and shown to grow at a normal rate. ...These results, in conjunction with DNA supercoiling measurements of others, indicate that in vivo DNA superhelicity is a result of …
Escherichia coli deletion mutants lacking DNA topoisomerase I have been identified previously and shown to grow at a normal rate. ... …
Poverty and Economic Dislocation Reduce Compliance with COVID-19 Shelter-in-Place Protocols.
Wright AL, Sonin K, Driscoll J, Wilson J. Wright AL, et al. J Econ Behav Organ. 2020 Oct 17. doi: 10.1016/j.jebo.2020.10.008. Online ahead of print. J Econ Behav Organ. 2020. PMID: 33100443 Free PMC article.
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