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A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in aotus monkeys.
Douglas AD, Baldeviano GC, Lucas CM, Lugo-Roman LA, Crosnier C, Bartholdson SJ, Diouf A, Miura K, Lambert LE, Ventocilla JA, Leiva KP, Milne KH, Illingworth JJ, Spencer AJ, Hjerrild KA, Alanine DG, Turner AV, Moorhead JT, Edgel KA, Wu Y, Long CA, Wright GJ, Lescano AG, Draper SJ. Douglas AD, et al. Among authors: wright gj. Cell Host Microbe. 2015 Jan 14;17(1):130-9. doi: 10.1016/j.chom.2014.11.017. Cell Host Microbe. 2015. PMID: 25590760 Free PMC article.
Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum.
Crosnier C, Bustamante LY, Bartholdson SJ, Bei AK, Theron M, Uchikawa M, Mboup S, Ndir O, Kwiatkowski DP, Duraisingh MT, Rayner JC, Wright GJ. Crosnier C, et al. Among authors: wright gj. Nature. 2011 Nov 9;480(7378):534-7. doi: 10.1038/nature10606. Nature. 2011. PMID: 22080952 Free PMC article.
Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens.
Williams AR, Douglas AD, Miura K, Illingworth JJ, Choudhary P, Murungi LM, Furze JM, Diouf A, Miotto O, Crosnier C, Wright GJ, Kwiatkowski DP, Fairhurst RM, Long CA, Draper SJ. Williams AR, et al. Among authors: wright gj. PLoS Pathog. 2012;8(11):e1002991. doi: 10.1371/journal.ppat.1002991. Epub 2012 Nov 8. PLoS Pathog. 2012. PMID: 23144611 Free PMC article.
173 results