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174 results
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Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity.
Axon A, May FE, Gaughan LE, Williams FM, Blain PG, Wright MC. Axon A, et al. Among authors: wright mc. Toxicology. 2012 Aug 16;298(1-3):40-51. doi: 10.1016/j.tox.2012.04.014. Epub 2012 May 3. Toxicology. 2012. PMID: 22562034
A mechanism for the anti-fibrogenic effects of the pregnane X receptor (PXR) in the liver: inhibition of NF-kappaB?
Axon A, Cowie DE, Mann DA, Wright MC. Axon A, et al. Among authors: wright mc. Toxicology. 2008 Apr 3;246(1):40-4. doi: 10.1016/j.tox.2007.12.008. Epub 2007 Dec 23. Toxicology. 2008. PMID: 18194834 Review.
Liver fibrosis.
Wallace K, Burt AD, Wright MC. Wallace K, et al. Among authors: wright mc. Biochem J. 2008 Apr 1;411(1):1-18. doi: 10.1042/BJ20071570. Biochem J. 2008. PMID: 18333835 Review.
Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury.
Douglass A, Wallace K, Parr R, Park J, Durward E, Broadbent I, Barelle C, Porter AJ, Wright MC. Douglass A, et al. Among authors: wright mc. J Hepatol. 2008 Jul;49(1):88-98. doi: 10.1016/j.jhep.2008.01.032. Epub 2008 Mar 13. J Hepatol. 2008. PMID: 18394744
Exocrine pancreas trans-differentiation to hepatocytes--a physiological response to elevated glucocorticoid in vivo.
Wallace K, Marek CJ, Currie RA, Wright MC. Wallace K, et al. Among authors: wright mc. J Steroid Biochem Mol Biol. 2009 Aug;116(1-2):76-85. doi: 10.1016/j.jsbmb.2009.05.002. Epub 2009 May 13. J Steroid Biochem Mol Biol. 2009. PMID: 19446026
A role for the pregnane X receptor in flucloxacillin-induced liver injury.
Andrews E, Armstrong M, Tugwood J, Swan D, Glaves P, Pirmohamed M, Aithal GP, Wright MC, Day CP, Daly AK. Andrews E, et al. Among authors: wright mc. Hepatology. 2010 May;51(5):1656-64. doi: 10.1002/hep.23549. Hepatology. 2010. PMID: 20222094
The PXR is a drug target for chronic inflammatory liver disease.
Wallace K, Cowie DE, Konstantinou DK, Hill SJ, Tjelle TE, Axon A, Koruth M, White SA, Carlsen H, Mann DA, Wright MC. Wallace K, et al. Among authors: wright mc. J Steroid Biochem Mol Biol. 2010 May 31;120(2-3):137-48. doi: 10.1016/j.jsbmb.2010.04.012. Epub 2010 Apr 21. J Steroid Biochem Mol Biol. 2010. PMID: 20416375 Free PMC article.
AR42J-B-13 cell: an expandable progenitor to generate an unlimited supply of functional hepatocytes.
Wallace K, Fairhall EA, Charlton KA, Wright MC. Wallace K, et al. Among authors: wright mc. Toxicology. 2010 Dec 30;278(3):277-87. doi: 10.1016/j.tox.2010.05.008. Epub 2010 Jun 1. Toxicology. 2010. PMID: 20685382 Review.
Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.
Ebrahimkhani MR, Oakley F, Murphy LB, Mann J, Moles A, Perugorria MJ, Ellis E, Lakey AF, Burt AD, Douglass A, Wright MC, White SA, Jaffré F, Maroteaux L, Mann DA. Ebrahimkhani MR, et al. Among authors: wright mc. Nat Med. 2011 Nov 27;17(12):1668-73. doi: 10.1038/nm.2490. Nat Med. 2011. PMID: 22120177 Free PMC article.
Utility of B-13 progenitor-derived hepatocytes in hepatotoxicity and genotoxicity studies.
Probert PM, Chung GW, Cockell SJ, Agius L, Mosesso P, White SA, Oakley F, Brown CD, Wright MC. Probert PM, et al. Among authors: wright mc. Toxicol Sci. 2014 Feb;137(2):350-70. doi: 10.1093/toxsci/kft258. Epub 2013 Nov 14. Toxicol Sci. 2014. PMID: 24235770 Free PMC article.
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