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Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.
MacLeod DT, Choi NM, Briney B, Garces F, Ver LS, Landais E, Murrell B, Wrin T, Kilembe W, Liang CH, Ramos A, Bian CB, Wickramasinghe L, Kong L, Eren K, Wu CY, Wong CH; IAVI Protocol C Investigators & The IAVI African HIV Research Network; Kosakovsky Pond SL, Wilson IA, Burton DR, Poignard P. MacLeod DT, et al. Among authors: wrin t. Immunity. 2016 May 17;44(5):1215-26. doi: 10.1016/j.immuni.2016.04.016. Immunity. 2016. PMID: 27192579 Free PMC article.
Reinfection with SARS-CoV-2 and Waning Humoral Immunity: A Case Report.
Goldman JD, Wang K, Röltgen K, Nielsen SCA, Roach JC, Naccache SN, Yang F, Wirz OF, Yost KE, Lee JY, Chun K, Wrin T, Petropoulos CJ, Lee I, Fallen S, Manner PM, Wallick JA, Algren HA, Murray KM, Hadlock J, Chen D, Dai CL, Yuan D, Su Y, Jeharajah J, Berrington WR, Pappas GP, Nyatsatsang ST, Greninger AL, Satpathy AT, Pauk JS, Boyd SD, Heath JR. Goldman JD, et al. Among authors: wrin t. Vaccines (Basel). 2022 Dec 20;11(1):5. doi: 10.3390/vaccines11010005. Vaccines (Basel). 2022. PMID: 36679852 Free PMC article.
Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1.
Labrijn AF, Poignard P, Raja A, Zwick MB, Delgado K, Franti M, Binley J, Vivona V, Grundner C, Huang CC, Venturi M, Petropoulos CJ, Wrin T, Dimitrov DS, Robinson J, Kwong PD, Wyatt RT, Sodroski J, Burton DR. Labrijn AF, et al. Among authors: wrin t. J Virol. 2003 Oct;77(19):10557-65. doi: 10.1128/jvi.77.19.10557-10565.2003. J Virol. 2003. PMID: 12970440 Free PMC article.
Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection.
Frost SD, Wrin T, Smith DM, Kosakovsky Pond SL, Liu Y, Paxinos E, Chappey C, Galovich J, Beauchaine J, Petropoulos CJ, Little SJ, Richman DD. Frost SD, et al. Among authors: wrin t. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18514-9. doi: 10.1073/pnas.0504658102. Epub 2005 Dec 9. Proc Natl Acad Sci U S A. 2005. PMID: 16339909 Free PMC article.
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm.
Simek MD, Rida W, Priddy FH, Pung P, Carrow E, Laufer DS, Lehrman JK, Boaz M, Tarragona-Fiol T, Miiro G, Birungi J, Pozniak A, McPhee DA, Manigart O, Karita E, Inwoley A, Jaoko W, Dehovitz J, Bekker LG, Pitisuttithum P, Paris R, Walker LM, Poignard P, Wrin T, Fast PE, Burton DR, Koff WC. Simek MD, et al. Among authors: wrin t. J Virol. 2009 Jul;83(14):7337-48. doi: 10.1128/JVI.00110-09. Epub 2009 May 13. J Virol. 2009. PMID: 19439467 Free PMC article.
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target.
Walker LM, Phogat SK, Chan-Hui PY, Wagner D, Phung P, Goss JL, Wrin T, Simek MD, Fling S, Mitcham JL, Lehrman JK, Priddy FH, Olsen OA, Frey SM, Hammond PW; Protocol G Principal Investigators; Kaminsky S, Zamb T, Moyle M, Koff WC, Poignard P, Burton DR. Walker LM, et al. Among authors: wrin t. Science. 2009 Oct 9;326(5950):285-9. doi: 10.1126/science.1178746. Epub 2009 Sep 3. Science. 2009. PMID: 19729618 Free PMC article.
Broad neutralization coverage of HIV by multiple highly potent antibodies.
Walker LM, Huber M, Doores KJ, Falkowska E, Pejchal R, Julien JP, Wang SK, Ramos A, Chan-Hui PY, Moyle M, Mitcham JL, Hammond PW, Olsen OA, Phung P, Fling S, Wong CH, Phogat S, Wrin T, Simek MD; Protocol G Principal Investigators; Koff WC, Wilson IA, Burton DR, Poignard P. Walker LM, et al. Among authors: wrin t. Nature. 2011 Sep 22;477(7365):466-70. doi: 10.1038/nature10373. Nature. 2011. PMID: 21849977 Free PMC article.
130 results