Wu B - Search Results

1

Use of physiologically based pharmacokinetic models to evaluate the impact of intestinal glucuronide hydrolysis on the pharmacokinetics of aglycone.

Wu B. Wu B. J Pharm Sci. 2012 Mar;101(3):1281-301. doi: 10.1002/jps.22827. Epub 2011 Nov 22. J Pharm Sci. 2012. PMID: 22109716

2

Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice.

Yang Z, Zhu W, Gao S, Xu H, Wu B, Kulkarni K, Singh R, Tang L, Hu M. Yang Z, et al. Among authors: wu b. J Pharm Biomed Anal. 2010 Sep 21;53(1):81-9. doi: 10.1016/j.jpba.2010.03.011. Epub 2010 Mar 16. J Pharm Biomed Anal. 2010. PMID: 20378296 Free PMC article.

3

Identification of the position of mono-O-glucuronide of flavones and flavonols by analyzing shift in online UV spectrum (lambdamax) generated from an online diode array detector.

Singh R, Wu B, Tang L, Liu Z, Hu M. Singh R, et al. Among authors: wu b. J Agric Food Chem. 2010 Sep 8;58(17):9384-95. doi: 10.1021/jf904561e. J Agric Food Chem. 2010. PMID: 20687611 Free PMC article.

4

Three-dimensional quantitative structure-activity relationship studies on UGT1A9-mediated 3-O-glucuronidation of natural flavonols using a pharmacophore-based comparative molecular field analysis model.

Wu B, Morrow JK, Singh R, Zhang S, Hu M. Wu B, et al. J Pharmacol Exp Ther. 2011 Feb;336(2):403-13. doi: 10.1124/jpet.110.175356. Epub 2010 Nov 10. J Pharmacol Exp Ther. 2011. PMID: 21068207 Free PMC article.

5

Uridine diphosphate glucuronosyltransferase isoform-dependent regiospecificity of glucuronidation of flavonoids.

Singh R, Wu B, Tang L, Hu M. Singh R, et al. Among authors: wu b. J Agric Food Chem. 2011 Jul 13;59(13):7452-64. doi: 10.1021/jf1041454. Epub 2011 Jun 6. J Agric Food Chem. 2011. PMID: 21413806 Free PMC article.

6

Regioselective glucuronidation of flavonols by six human UGT1A isoforms.

Wu B, Xu B, Hu M. Wu B, et al. Pharm Res. 2011 Aug;28(8):1905-18. doi: 10.1007/s11095-011-0418-5. Epub 2011 Apr 7. Pharm Res. 2011. PMID: 21472492 Free PMC article.

7

First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics.

Wu B, Kulkarni K, Basu S, Zhang S, Hu M. Wu B, et al. J Pharm Sci. 2011 Sep;100(9):3655-81. doi: 10.1002/jps.22568. Epub 2011 Apr 11. J Pharm Sci. 2011. PMID: 21484808 Free PMC article. Review.

8

Enhancement of oral bioavailability of 20(S)-ginsenoside Rh2 through improved understanding of its absorption and efflux mechanisms.

Yang Z, Gao S, Wang J, Yin T, Teng Y, Wu B, You M, Jiang Z, Hu M. Yang Z, et al. Among authors: wu b. Drug Metab Dispos. 2011 Oct;39(10):1866-72. doi: 10.1124/dmd.111.040006. Epub 2011 Jul 14. Drug Metab Dispos. 2011. PMID: 21757611

9

Pharmacokinetic interplay of phase II metabolism and transport: a theoretical study.

Wu B. Wu B. J Pharm Sci. 2012 Jan;101(1):381-93. doi: 10.1002/jps.22738. Epub 2011 Sep 8. J Pharm Sci. 2012. PMID: 21905031

10

Regioselective sulfation and glucuronidation of phenolics: insights into the structural basis.

Wu B, Basu S, Meng S, Wang X, Hu M. Wu B, et al. Curr Drug Metab. 2011 Nov;12(9):900-16. doi: 10.2174/138920011797470100. Curr Drug Metab. 2011. PMID: 21933112 Free PMC article. Review.

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