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2,370 results
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Sex-related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P-glycoprotein.
Cummins CL, Wu CY, Benet LZ. Cummins CL, et al. Among authors: wu cy. Clin Pharmacol Ther. 2002 Nov;72(5):474-89. doi: 10.1067/mcp.2002.128388. Clin Pharmacol Ther. 2002. PMID: 12426511 Review. No abstract available.
Ex situ inhibition of hepatic uptake and efflux significantly changes metabolism: hepatic enzyme-transporter interplay.
Lau YY, Wu CY, Okochi H, Benet LZ. Lau YY, et al. Among authors: wu cy. J Pharmacol Exp Ther. 2004 Mar;308(3):1040-5. doi: 10.1124/jpet.103.061770. Epub 2003 Nov 21. J Pharmacol Exp Ther. 2004. PMID: 14634033
Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine.
Wu CY, Benet LZ, Hebert MF, Gupta SK, Rowland M, Gomez DY, Wacher VJ. Wu CY, et al. Clin Pharmacol Ther. 1995 Nov;58(5):492-7. doi: 10.1016/0009-9236(95)90168-X. Clin Pharmacol Ther. 1995. PMID: 7586942
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.
Wacher VJ, Wu CY, Benet LZ. Wacher VJ, et al. Among authors: wu cy. Mol Carcinog. 1995 Jul;13(3):129-34. doi: 10.1002/mc.2940130302. Mol Carcinog. 1995. PMID: 7619215 Review. No abstract available.
Transporter-enzyme interactions: implications for predicting drug-drug interactions from in vitro data.
Benet LZ, Cummins CL, Wu CY. Benet LZ, et al. Among authors: wu cy. Curr Drug Metab. 2003 Oct;4(5):393-8. doi: 10.2174/1389200033489389. Curr Drug Metab. 2003. PMID: 14529371 Review.
Unmasking the dynamic interplay between efflux transporters and metabolic enzymes.
Benet LZ, Cummins CL, Wu CY. Benet LZ, et al. Among authors: wu cy. Int J Pharm. 2004 Jun 11;277(1-2):3-9. doi: 10.1016/j.ijpharm.2002.12.002. Int J Pharm. 2004. PMID: 15158963 Review.
Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system.
Wu CY, Benet LZ. Wu CY, et al. Pharm Res. 2005 Jan;22(1):11-23. doi: 10.1007/s11095-004-9004-4. Pharm Res. 2005. PMID: 15771225 Review.
Disposition of tacrolimus in isolated perfused rat liver: influence of troleandomycin, cyclosporine, and gg918.
Wu CY, Benet LZ. Wu CY, et al. Drug Metab Dispos. 2003 Nov;31(11):1292-5. doi: 10.1124/dmd.31.11.1292. Drug Metab Dispos. 2003. PMID: 14570757
Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption.
Custodio JM, Wu CY, Benet LZ. Custodio JM, et al. Among authors: wu cy. Adv Drug Deliv Rev. 2008 Mar 17;60(6):717-33. doi: 10.1016/j.addr.2007.08.043. Epub 2007 Nov 28. Adv Drug Deliv Rev. 2008. PMID: 18199522 Free PMC article. Review.
Comparison of digitized images with original radiography for semiquantitative assessment of osteoporotic fractures.
Wu C, van Kuijk C, Li J, Jiang Y, Chan M, Countryman P, Genant HK. Wu C, et al. Osteoporos Int. 2000;11(1):25-30. doi: 10.1007/s001980050002. Osteoporos Int. 2000. PMID: 10663355
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