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2,369 results
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Unmasking the dynamic interplay between efflux transporters and metabolic enzymes.
Benet LZ, Cummins CL, Wu CY. Benet LZ, et al. Among authors: wu cy. Int J Pharm. 2004 Jun 11;277(1-2):3-9. doi: 10.1016/j.ijpharm.2002.12.002. Int J Pharm. 2004. PMID: 15158963 Review.
Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption.
Custodio JM, Wu CY, Benet LZ. Custodio JM, et al. Among authors: wu cy. Adv Drug Deliv Rev. 2008 Mar 17;60(6):717-33. doi: 10.1016/j.addr.2007.08.043. Epub 2007 Nov 28. Adv Drug Deliv Rev. 2008. PMID: 18199522 Free PMC article. Review.
Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system.
Wu CY, Benet LZ. Wu CY, et al. Pharm Res. 2005 Jan;22(1):11-23. doi: 10.1007/s11095-004-9004-4. Pharm Res. 2005. PMID: 15771225 Review.
Disposition of tacrolimus in isolated perfused rat liver: influence of troleandomycin, cyclosporine, and gg918.
Wu CY, Benet LZ. Wu CY, et al. Drug Metab Dispos. 2003 Nov;31(11):1292-5. doi: 10.1124/dmd.31.11.1292. Drug Metab Dispos. 2003. PMID: 14570757
Sex-related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P-glycoprotein.
Cummins CL, Wu CY, Benet LZ. Cummins CL, et al. Among authors: wu cy. Clin Pharmacol Ther. 2002 Nov;72(5):474-89. doi: 10.1067/mcp.2002.128388. Clin Pharmacol Ther. 2002. PMID: 12426511 Review. No abstract available.
Ex situ inhibition of hepatic uptake and efflux significantly changes metabolism: hepatic enzyme-transporter interplay.
Lau YY, Wu CY, Okochi H, Benet LZ. Lau YY, et al. Among authors: wu cy. J Pharmacol Exp Ther. 2004 Mar;308(3):1040-5. doi: 10.1124/jpet.103.061770. Epub 2003 Nov 21. J Pharmacol Exp Ther. 2004. PMID: 14634033
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.
Wacher VJ, Wu CY, Benet LZ. Wacher VJ, et al. Among authors: wu cy. Mol Carcinog. 1995 Jul;13(3):129-34. doi: 10.1002/mc.2940130302. Mol Carcinog. 1995. PMID: 7619215 Review. No abstract available.
Transporter-enzyme interactions: implications for predicting drug-drug interactions from in vitro data.
Benet LZ, Cummins CL, Wu CY. Benet LZ, et al. Among authors: wu cy. Curr Drug Metab. 2003 Oct;4(5):393-8. doi: 10.2174/1389200033489389. Curr Drug Metab. 2003. PMID: 14529371 Review.
Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine.
Wu CY, Benet LZ, Hebert MF, Gupta SK, Rowland M, Gomez DY, Wacher VJ. Wu CY, et al. Clin Pharmacol Ther. 1995 Nov;58(5):492-7. doi: 10.1016/0009-9236(95)90168-X. Clin Pharmacol Ther. 1995. PMID: 7586942
Vertebral fracture assessment using the lateral scoutview of computed tomography in comparison with radiographs.
Takada M, Wu CY, Lang TF, Genant HK. Takada M, et al. Among authors: wu cy. Osteoporos Int. 1998;8(3):197-203. doi: 10.1007/s001980050054. Osteoporos Int. 1998. PMID: 9797902
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