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Small molecules targeting severe acute respiratory syndrome human coronavirus.

Wu CY, Jan JT, Ma SH, Kuo CJ, Juan HF, Cheng YS, Hsu HH, Huang HC, Wu D, Brik A, Liang FS, Liu RS, Fang JM, Chen ST, Liang PH, Wong CH. Wu CY, et al. Among authors: Wu D. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10012-7. doi: 10.1073/pnas.0403596101. Epub 2004 Jun 28. Proc Natl Acad Sci U S A. 2004. PMID: 15226499 Free PMC article.

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Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors.

Wu CY, Chang CF, Chen JS, Wong CH, Lin CH. Wu CY, et al. Angew Chem Int Ed Engl. 2003 Oct 6;42(38):4661-4. doi: 10.1002/anie.200351823. Angew Chem Int Ed Engl. 2003. PMID: 14533157 No abstract available.

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3

Discovery of picomolar slow tight-binding inhibitors of alpha-fucosidase.

Chang CF, Ho CW, Wu CY, Chao TA, Wong CH, Lin CH. Chang CF, et al. Among authors: Wu CY. Chem Biol. 2004 Sep;11(9):1301-6. doi: 10.1016/j.chembiol.2004.07.009. Chem Biol. 2004. PMID: 15380190

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4

Stable benzotriazole esters as mechanism-based inactivators of the severe acute respiratory syndrome 3CL protease.

Wu CY, King KY, Kuo CJ, Fang JM, Wu YT, Ho MY, Liao CL, Shie JJ, Liang PH, Wong CH. Wu CY, et al. Among authors: Wu YT. Chem Biol. 2006 Mar;13(3):261-8. doi: 10.1016/j.chembiol.2005.12.008. Chem Biol. 2006. PMID: 16638531 Free PMC article.

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5

Discovery of different types of inhibition between the human and thermotoga maritima alpha-fucosidases by fuconojirimycin-based derivatives.

Ho CW, Lin YN, Chang CF, Li ST, Wu YT, Wu CY, Chang CF, Liu SW, Li YK, Lin CH. Ho CW, et al. Among authors: Wu YT, Wu CY. Biochemistry. 2006 May 9;45(18):5695-702. doi: 10.1021/bi052559n. Biochemistry. 2006. PMID: 16669613

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6

Glycan microarray of Globo H and related structures for quantitative analysis of breast cancer.

Wang CC, Huang YL, Ren CT, Lin CW, Hung JT, Yu JC, Yu AL, Wu CY, Wong CH. Wang CC, et al. Among authors: Wu CY. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11661-6. doi: 10.1073/pnas.0804923105. Epub 2008 Aug 8. Proc Natl Acad Sci U S A. 2008. PMID: 18689688 Free PMC article.

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7

Glycans on influenza hemagglutinin affect receptor binding and immune response.

Wang CC, Chen JR, Tseng YC, Hsu CH, Hung YF, Chen SW, Chen CM, Khoo KH, Cheng TJ, Cheng YS, Jan JT, Wu CY, Ma C, Wong CH. Wang CC, et al. Among authors: Wu CY. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18137-42. doi: 10.1073/pnas.0909696106. Epub 2009 Oct 12. Proc Natl Acad Sci U S A. 2009. PMID: 19822741 Free PMC article.

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8

High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity.

Su CY, Cheng TJ, Lin MI, Wang SY, Huang WI, Lin-Chu SY, Chen YH, Wu CY, Lai MM, Cheng WC, Wu YT, Tsai MD, Cheng YS, Wong CH. Su CY, et al. Among authors: Wu CY, Wu YT. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19151-6. doi: 10.1073/pnas.1013592107. Epub 2010 Oct 25. Proc Natl Acad Sci U S A. 2010. PMID: 20974907 Free PMC article.

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9

The SUMOylation of matrix protein M1 modulates the assembly and morphogenesis of influenza A virus.

Wu CY, Jeng KS, Lai MM. Wu CY, et al. J Virol. 2011 Jul;85(13):6618-28. doi: 10.1128/JVI.02401-10. Epub 2011 Apr 20. J Virol. 2011. PMID: 21507966 Free PMC article.

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10

Chemical probes for drug-resistance assessment by binding competition (RABC): oseltamivir susceptibility evaluation.

Cheng TJ, Wang SY, Wen WH, Su CY, Lin M, Huang WI, Liu MT, Wu HS, Wang NS, Cheng CK, Chen CL, Ren CT, Wu CY, Fang JM, Cheng YS, Wong CH. Cheng TJ, et al. Among authors: Wu HS, Wu CY. Angew Chem Int Ed Engl. 2013 Jan 2;52(1):366-70. doi: 10.1002/anie.201204062. Epub 2012 Nov 13. Angew Chem Int Ed Engl. 2013. PMID: 23150231

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