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Cancer stem cells.
Guo W, Lasky JL 3rd, Wu H. Guo W, et al. Among authors: wu h. Pediatr Res. 2006 Apr;59(4 Pt 2):59R-64R. doi: 10.1203/01.pdr.0000203592.04530.06. Pediatr Res. 2006. PMID: 16549550 Review.
PTEN-deficient intestinal stem cells initiate intestinal polyposis.
He XC, Yin T, Grindley JC, Tian Q, Sato T, Tao WA, Dirisina R, Porter-Westpfahl KS, Hembree M, Johnson T, Wiedemann LM, Barrett TA, Hood L, Wu H, Li L. He XC, et al. Among authors: wu h. Nat Genet. 2007 Feb;39(2):189-98. doi: 10.1038/ng1928. Epub 2007 Jan 21. Nat Genet. 2007. PMID: 17237784 Free PMC article.
Suppression of leukemia development caused by PTEN loss.
Guo W, Schubbert S, Chen JY, Valamehr B, Mosessian S, Shi H, Dang NH, Garcia C, Theodoro MF, Varella-Garcia M, Wu H. Guo W, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1409-14. doi: 10.1073/pnas.1006937108. Epub 2011 Jan 6. Proc Natl Acad Sci U S A. 2011. PMID: 21212363 Free PMC article.
PTEN opposes negative selection and enables oncogenic transformation of pre-B cells.
Shojaee S, Chan LN, Buchner M, Cazzaniga V, Cosgun KN, Geng H, Qiu YH, von Minden MD, Ernst T, Hochhaus A, Cazzaniga G, Melnick A, Kornblau SM, Graeber TG, Wu H, Jumaa H, Müschen M. Shojaee S, et al. Among authors: wu h. Nat Med. 2016 Apr;22(4):379-87. doi: 10.1038/nm.4062. Epub 2016 Mar 14. Nat Med. 2016. PMID: 26974310 Free PMC article.
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