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46,438 results
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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.
Inoki K, Li Y, Zhu T, Wu J, Guan KL. Inoki K, et al. Among authors: wu j. Nat Cell Biol. 2002 Sep;4(9):648-57. doi: 10.1038/ncb839. Nat Cell Biol. 2002. PMID: 12172553
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response.
Zhang K, Shen X, Wu J, Sakaki K, Saunders T, Rutkowski DT, Back SH, Kaufman RJ. Zhang K, et al. Among authors: wu j. Cell. 2006 Feb 10;124(3):587-99. doi: 10.1016/j.cell.2005.11.040. Cell. 2006. PMID: 16469704
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins.
Rutkowski DT, Arnold SM, Miller CN, Wu J, Li J, Gunnison KM, Mori K, Sadighi Akha AA, Raden D, Kaufman RJ. Rutkowski DT, et al. Among authors: wu j. PLoS Biol. 2006 Nov;4(11):e374. doi: 10.1371/journal.pbio.0040374. PLoS Biol. 2006. PMID: 17090218 Free PMC article.
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress.
Wu J, Rutkowski DT, Dubois M, Swathirajan J, Saunders T, Wang J, Song B, Yau GD, Kaufman RJ. Wu J, et al. Dev Cell. 2007 Sep;13(3):351-64. doi: 10.1016/j.devcel.2007.07.005. Dev Cell. 2007. PMID: 17765679
Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulum.
Sakaki K, Wu J, Kaufman RJ. Sakaki K, et al. Among authors: wu j. J Biol Chem. 2008 May 30;283(22):15370-80. doi: 10.1074/jbc.M710209200. Epub 2008 Mar 20. J Biol Chem. 2008. PMID: 18356160 Free PMC article.
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.
Rutkowski DT, Wu J, Back SH, Callaghan MU, Ferris SP, Iqbal J, Clark R, Miao H, Hassler JR, Fornek J, Katze MG, Hussain MM, Song B, Swathirajan J, Wang J, Yau GD, Kaufman RJ. Rutkowski DT, et al. Among authors: wu j. Dev Cell. 2008 Dec;15(6):829-40. doi: 10.1016/j.devcel.2008.10.015. Dev Cell. 2008. PMID: 19081072 Free PMC article.
Development, activation, and therapeutic potential of thermogenic adipocytes.
Emont MP, Kim DI, Wu J. Emont MP, et al. Among authors: wu j. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jan;1864(1):13-19. doi: 10.1016/j.bbalip.2018.05.004. Epub 2018 May 22. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 29763732 Free PMC article. Review.
An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling.
Jun H, Yu H, Gong J, Jiang J, Qiao X, Perkey E, Kim DI, Emont MP, Zestos AG, Cho JS, Liu J, Kennedy RT, Maillard I, Xu XZS, Wu J. Jun H, et al. Among authors: wu j. Nat Med. 2018 Jun;24(6):814-822. doi: 10.1038/s41591-018-0032-8. Epub 2018 May 21. Nat Med. 2018. PMID: 29785025 Free PMC article.
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.
Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G, Garcia ME, Launer LJ, Nalls MA, Clark JM, Mitchell BD, Shuldiner AR, Butler JL, Tomas M, Hoffmann U, Hwang SJ, Massaro JM, O'Donnell CJ, Sahani DV, Salomaa V, Schadt EE, Schwartz SM, Siscovick DS; NASH CRN; GIANT Consortium; MAGIC Investigators, Voight BF, Carr JJ, Feitosa MF, Harris TB, Fox CS, Smith AV, Kao WH, Hirschhorn JN, Borecki IB; GOLD Consortium. Speliotes EK, et al. Among authors: wu j. PLoS Genet. 2011 Mar;7(3):e1001324. doi: 10.1371/journal.pgen.1001324. Epub 2011 Mar 10. PLoS Genet. 2011. PMID: 21423719 Free PMC article.
Adrenergic-Independent Signaling via CHRNA2 Regulates Beige Fat Activation.
Jun H, Ma Y, Chen Y, Gong J, Liu S, Wang J, Knights AJ, Qiao X, Emont MP, Xu XZS, Kajimura S, Wu J. Jun H, et al. Among authors: wu j. Dev Cell. 2020 Jul 6;54(1):106-116.e5. doi: 10.1016/j.devcel.2020.05.017. Epub 2020 Jun 12. Dev Cell. 2020. PMID: 32533922
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