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FDA-approved small-molecule kinase inhibitors.
Wu P, Nielsen TE, Clausen MH. Wu P, et al. Trends Pharmacol Sci. 2015 Jul;36(7):422-39. doi: 10.1016/j.tips.2015.04.005. Epub 2015 May 12. Trends Pharmacol Sci. 2015. PMID: 25975227 Review.
Synthesis of 1,4,5 trisubstituted γ-lactams via a 3-component cascade reaction.
Petersen MÅ, Mortensen MA, Cohrt AE, Petersen R, Wu P, Fleury-Brégeot N, Morgentin R, Lardy C, Nielsen TE, Clausen MH. Petersen MÅ, et al. Among authors: wu p. Bioorg Med Chem. 2015 Jun 1;23(11):2695-8. doi: 10.1016/j.bmc.2015.01.041. Epub 2015 Jan 31. Bioorg Med Chem. 2015. PMID: 25684425
Allosteric small-molecule kinase inhibitors.
Wu P, Clausen MH, Nielsen TE. Wu P, et al. Pharmacol Ther. 2015 Dec;156:59-68. doi: 10.1016/j.pharmthera.2015.10.002. Epub 2015 Oct 24. Pharmacol Ther. 2015. PMID: 26478442 Review.
Scaffold Diversity from N-Acyliminium Ions.
Wu P, Nielsen TE. Wu P, et al. Chem Rev. 2017 Jun 28;117(12):7811-7856. doi: 10.1021/acs.chemrev.6b00806. Epub 2017 May 11. Chem Rev. 2017. PMID: 28493667
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