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Cryo-EM structures of apo and antagonist-bound human Cav3.1.
Zhao Y, Huang G, Wu Q, Wu K, Li R, Lei J, Pan X, Yan N. Zhao Y, et al. Among authors: wu q, wu k. Nature. 2019 Dec;576(7787):492-497. doi: 10.1038/s41586-019-1801-3. Epub 2019 Nov 25. Nature. 2019. PMID: 31766050
Structural mapping of Nav1.7 antagonists.
Wu Q, Huang J, Fan X, Wang K, Jin X, Huang G, Li J, Pan X, Yan N. Wu Q, et al. Nat Commun. 2023 Jun 3;14(1):3224. doi: 10.1038/s41467-023-38942-3. Nat Commun. 2023. PMID: 37270609 Free PMC article.
A structural atlas of druggable sites on Nav channels.
Li Z, Wu Q, Yan N. Li Z, et al. Among authors: wu q. Channels (Austin). 2024 Dec;18(1):2287832. doi: 10.1080/19336950.2023.2287832. Epub 2023 Nov 30. Channels (Austin). 2024. PMID: 38033122 Free PMC article. Review.
Dissection of the structure-function relationship of Nav channels.
Li Z, Wu Q, Huang G, Jin X, Li J, Pan X, Yan N. Li Z, et al. Among authors: wu q. Proc Natl Acad Sci U S A. 2024 Feb 27;121(9):e2322899121. doi: 10.1073/pnas.2322899121. Epub 2024 Feb 21. Proc Natl Acad Sci U S A. 2024. PMID: 38381792
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