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Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing.
Dan J, Liu Y, Liu N, Chiourea M, Okuka M, Wu T, Ye X, Mou C, Wang L, Wang L, Yin Y, Yuan J, Zuo B, Wang F, Li Z, Pan X, Yin Z, Chen L, Keefe DL, Gagos S, Xiao A, Liu L. Dan J, et al. Among authors: wu t. Dev Cell. 2014 Apr 14;29(1):7-19. doi: 10.1016/j.devcel.2014.03.004. Dev Cell. 2014. PMID: 24735877 Free PMC article.
Histone variant H2A.X deposition pattern serves as a functional epigenetic mark for distinguishing the developmental potentials of iPSCs.
Wu T, Liu Y, Wen D, Tseng Z, Tahmasian M, Zhong M, Rafii S, Stadtfeld M, Hochedlinger K, Xiao A. Wu T, et al. Cell Stem Cell. 2014 Sep 4;15(3):281-294. doi: 10.1016/j.stem.2014.06.004. Cell Stem Cell. 2014. PMID: 25192463
The developmental potential of iPSCs is greatly influenced by reprogramming factor selection.
Buganim Y, Markoulaki S, van Wietmarschen N, Hoke H, Wu T, Ganz K, Akhtar-Zaidi B, He Y, Abraham BJ, Porubsky D, Kulenkampff E, Faddah DA, Shi L, Gao Q, Sarkar S, Cohen M, Goldmann J, Nery JR, Schultz MD, Ecker JR, Xiao A, Young RA, Lansdorp PM, Jaenisch R. Buganim Y, et al. Among authors: wu t. Cell Stem Cell. 2014 Sep 4;15(3):295-309. doi: 10.1016/j.stem.2014.07.003. Cell Stem Cell. 2014. PMID: 25192464 Free PMC article.
Extensive Nuclear Reprogramming Underlies Lineage Conversion into Functional Trophoblast Stem-like Cells.
Benchetrit H, Herman S, van Wietmarschen N, Wu T, Makedonski K, Maoz N, Yom Tov N, Stave D, Lasry R, Zayat V, Xiao A, Lansdorp PM, Sebban S, Buganim Y. Benchetrit H, et al. Among authors: wu t. Cell Stem Cell. 2015 Nov 5;17(5):543-56. doi: 10.1016/j.stem.2015.08.006. Epub 2015 Sep 24. Cell Stem Cell. 2015. PMID: 26412562
DNA methylation on N(6)-adenine in mammalian embryonic stem cells.
Wu TP, Wang T, Seetin MG, Lai Y, Zhu S, Lin K, Liu Y, Byrum SD, Mackintosh SG, Zhong M, Tackett A, Wang G, Hon LS, Fang G, Swenberg JA, Xiao AZ. Wu TP, et al. Nature. 2016 Apr 21;532(7599):329-33. doi: 10.1038/nature17640. Epub 2016 Mar 30. Nature. 2016. PMID: 27027282 Free PMC article.
Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing.
Zhu S, Beaulaurier J, Deikus G, Wu TP, Strahl M, Hao Z, Luo G, Gregory JA, Chess A, He C, Xiao A, Sebra R, Schadt EE, Fang G. Zhu S, et al. Among authors: wu tp. Genome Res. 2018 Jul;28(7):1067-1078. doi: 10.1101/gr.231068.117. Epub 2018 May 15. Genome Res. 2018. PMID: 29764913 Free PMC article.
N6-methyladenine in DNA antagonizes SATB1 in early development.
Li Z, Zhao S, Nelakanti RV, Lin K, Wu TP, Alderman MH 3rd, Guo C, Wang P, Zhang M, Min W, Jiang Z, Wang Y, Li H, Xiao AZ. Li Z, et al. Among authors: wu tp. Nature. 2020 Jul;583(7817):625-630. doi: 10.1038/s41586-020-2500-9. Epub 2020 Jul 15. Nature. 2020. PMID: 32669713
Sequential chromatin immunoprecipitation to detect SUMOylated MeCP2 in neurons.
Wu T, Donohoe ME. Wu T, et al. Biochem Biophys Rep. 2016 Mar;5:374-378. doi: 10.1016/j.bbrep.2016.01.014. Epub 2016 Jan 23. Biochem Biophys Rep. 2016. PMID: 28944302 Free PMC article.
Mammalian ALKBH1 serves as an N6-mA demethylase of unpairing DNA.
Zhang M, Yang S, Nelakanti R, Zhao W, Liu G, Li Z, Liu X, Wu T, Xiao A, Li H. Zhang M, et al. Among authors: wu t. Cell Res. 2020 Mar;30(3):197-210. doi: 10.1038/s41422-019-0237-5. Epub 2020 Feb 12. Cell Res. 2020. PMID: 32051560 Free PMC article.
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