Wu Y - Search Results

1

De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures.

Dang B, Wu H, Mulligan VK, Mravic M, Wu Y, Lemmin T, Ford A, Silva DA, Baker D, DeGrado WF. Dang B, et al. Among authors: wu y, wu h. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10852-10857. doi: 10.1073/pnas.1710695114. Epub 2017 Sep 25. Proc Natl Acad Sci U S A. 2017. PMID: 28973862 Free PMC article.

2

Consistent blind protein structure generation from NMR chemical shift data.

Shen Y, Lange O, Delaglio F, Rossi P, Aramini JM, Liu G, Eletsky A, Wu Y, Singarapu KK, Lemak A, Ignatchenko A, Arrowsmith CH, Szyperski T, Montelione GT, Baker D, Bax A. Shen Y, et al. Among authors: wu y. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4685-90. doi: 10.1073/pnas.0800256105. Epub 2008 Mar 7. Proc Natl Acad Sci U S A. 2008. PMID: 18326625 Free PMC article.

3

Simultaneous prediction of protein folding and docking at high resolution.

Das R, André I, Shen Y, Wu Y, Lemak A, Bansal S, Arrowsmith CH, Szyperski T, Baker D. Das R, et al. Among authors: wu y. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):18978-83. doi: 10.1073/pnas.0904407106. Epub 2009 Oct 28. Proc Natl Acad Sci U S A. 2009. PMID: 19864631 Free PMC article.

4

NMR analysis of the alphaIIb beta3 cytoplasmic interaction suggests a mechanism for integrin regulation.

Metcalf DG, Moore DT, Wu Y, Kielec JM, Molnar K, Valentine KG, Wand AJ, Bennett JS, DeGrado WF. Metcalf DG, et al. Among authors: wu y. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22481-6. doi: 10.1073/pnas.1015545107. Epub 2010 Dec 14. Proc Natl Acad Sci U S A. 2010. PMID: 21156831 Free PMC article.

5

Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy.

Cady SD, Wang J, Wu Y, DeGrado WF, Hong M. Cady SD, et al. Among authors: wu y. J Am Chem Soc. 2011 Mar 30;133(12):4274-84. doi: 10.1021/ja102581n. Epub 2011 Mar 7. J Am Chem Soc. 2011. PMID: 21381693 Free PMC article.

6

Design of a switchable eliminase.

Korendovych IV, Kulp DW, Wu Y, Cheng H, Roder H, DeGrado WF. Korendovych IV, et al. Among authors: wu y. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6823-7. doi: 10.1073/pnas.1018191108. Epub 2011 Apr 11. Proc Natl Acad Sci U S A. 2011. PMID: 21482808 Free PMC article.

7

Residue-specific vibrational echoes yield 3D structures of a transmembrane helix dimer.

Remorino A, Korendovych IV, Wu Y, DeGrado WF, Hochstrasser RM. Remorino A, et al. Among authors: wu y. Science. 2011 Jun 3;332(6034):1206-9. doi: 10.1126/science.1202997. Science. 2011. PMID: 21636774 Free PMC article.

8

Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel.

Wang J, Ma C, Wu Y, Lamb RA, Pinto LH, DeGrado WF. Wang J, et al. Among authors: wu y. J Am Chem Soc. 2011 Sep 7;133(35):13844-7. doi: 10.1021/ja2050666. Epub 2011 Aug 12. J Am Chem Soc. 2011. PMID: 21819109 Free PMC article.

9

Development of α-helical calpain probes by mimicking a natural protein-protein interaction.

Jo H, Meinhardt N, Wu Y, Kulkarni S, Hu X, Low KE, Davies PL, DeGrado WF, Greenbaum DC. Jo H, et al. Among authors: wu y. J Am Chem Soc. 2012 Oct 24;134(42):17704-13. doi: 10.1021/ja307599z. Epub 2012 Oct 11. J Am Chem Soc. 2012. PMID: 22998171 Free PMC article.

10

Alteration of the oxygen-dependent reactivity of de novo Due Ferri proteins.

Reig AJ, Pires MM, Snyder RA, Wu Y, Jo H, Kulp DW, Butch SE, Calhoun JR, Szyperski T, Solomon EI, DeGrado WF. Reig AJ, et al. Among authors: wu y. Nat Chem. 2012 Nov;4(11):900-6. doi: 10.1038/nchem.1454. Epub 2012 Sep 23. Nat Chem. 2012. PMID: 23089864 Free PMC article.

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