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Toll-like receptors: potential targets for lupus treatment.
Wu YW, Tang W, Zuo JP. Wu YW, et al. Acta Pharmacol Sin. 2015 Dec;36(12):1395-407. doi: 10.1038/aps.2015.91. Epub 2015 Nov 23. Acta Pharmacol Sin. 2015. PMID: 26592511 Free PMC article. Review.
Therapeutic effects of DZ2002, a reversible SAHH inhibitor, on lupus-prone NZB├ŚNZW F1 mice via interference with TLR-mediated APC response.
He SJ, Lin ZM, Wu YW, Bai BX, Yang XQ, He PL, Zhu FH, Tang W, Zuo JP. He SJ, et al. Among authors: wu yw. Acta Pharmacol Sin. 2014 Feb;35(2):219-29. doi: 10.1038/aps.2013.167. Epub 2013 Dec 30. Acta Pharmacol Sin. 2014. PMID: 24374810 Free PMC article.
Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation.
Wu Y, He S, Bai B, Zhang L, Xue L, Lin Z, Yang X, Zhu F, He P, Tang W, Zuo J. Wu Y, et al. Cell Mol Immunol. 2016 May;13(3):379-90. doi: 10.1038/cmi.2015.13. Epub 2015 Mar 16. Cell Mol Immunol. 2016. PMID: 25942599 Free PMC article.
(5R)-5-hydroxytriptolide ameliorates lupus nephritis in MRL/lpr mice by preventing infiltration of immune cells.
Zhang LY, Li H, Wu YW, Cheng L, Yan YX, Yang XQ, Zhu FH, He SJ, Tang W, Zuo JP. Zhang LY, et al. Among authors: wu yw. Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F769-F777. doi: 10.1152/ajprenal.00649.2016. Epub 2017 Jan 18. Am J Physiol Renal Physiol. 2017. PMID: 28100505
Artemisinin analogue SM934 ameliorates DSS-induced mouse ulcerative colitis via suppressing neutrophils and macrophages.
Yan YX, Shao MJ, Qi Q, Xu YS, Yang XQ, Zhu FH, He SJ, He PL, Feng CL, Wu YW, Li H, Tang W, Zuo JP. Yan YX, et al. Among authors: wu yw. Acta Pharmacol Sin. 2018 Oct;39(10):1633-1644. doi: 10.1038/aps.2017.185. Epub 2018 May 31. Acta Pharmacol Sin. 2018. PMID: 29849131 Free PMC article.
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way.
Wu Y, Wu B, Zhang Z, Lu H, Fan C, Qi Q, Gao Y, Li H, Feng C, Zuo J, Tang W. Wu Y, et al. Among authors: wu b. FASEB J. 2020 Jun;34(6):8028-8043. doi: 10.1096/fj.202000313RR. Epub 2020 Apr 17. FASEB J. 2020. PMID: 32301543
Heme Catabolic Pathway in Inflammation and Immune Disorders.
Wu B, Wu Y, Tang W. Wu B, et al. Among authors: wu y. Front Pharmacol. 2019 Jul 24;10:825. doi: 10.3389/fphar.2019.00825. eCollection 2019. Front Pharmacol. 2019. PMID: 31396090 Free PMC article. Review.
RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk.
Lu H, Li H, Fan C, Qi Q, Yan Y, Wu Y, Feng C, Wu B, Gao Y, Zuo J, Tang W. Lu H, et al. Among authors: wu y, wu b. Biochem Pharmacol. 2020 Feb;172:113751. doi: 10.1016/j.bcp.2019.113751. Epub 2019 Dec 16. Biochem Pharmacol. 2020. PMID: 31837309
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models.
Zhang Z, Wu Y, Wu B, Qi Q, Li H, Lu H, Fan C, Feng C, Zuo J, Niu L, Tang W. Zhang Z, et al. Among authors: wu y, wu b. Arthritis Res Ther. 2019 Dec 16;21(1):290. doi: 10.1186/s13075-019-2074-9. Arthritis Res Ther. 2019. PMID: 31842999 Free PMC article.
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity.
Li H, Fan C, Feng C, Wu Y, Lu H, He P, Yang X, Zhu F, Qi Q, Gao Y, Zuo J, Tang W. Li H, et al. Among authors: wu y. Br J Pharmacol. 2019 Jul;176(13):2209-2226. doi: 10.1111/bph.14667. Epub 2019 May 17. Br J Pharmacol. 2019. PMID: 30883697 Free PMC article.
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