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eQTL Epistasis - Challenges and Computational Approaches.
Huang Y, Wuchty S, Przytycka TM. Huang Y, et al. Among authors: wuchty s. Front Genet. 2013 May 31;4:51. doi: 10.3389/fgene.2013.00051. eCollection 2013. Front Genet. 2013. PMID: 23755066 Free PMC article.
Computational prediction of host-parasite protein interactions between P. falciparum and H. sapiens.
Wuchty S. Wuchty S. PLoS One. 2011;6(11):e26960. doi: 10.1371/journal.pone.0026960. Epub 2011 Nov 17. PLoS One. 2011. PMID: 22114664 Free PMC article.
Computational large-scale mapping of protein-protein interactions using structural complexes.
Shoemaker B, Wuchty S, Panchenko AR. Shoemaker B, et al. Among authors: wuchty s. Curr Protoc Protein Sci. 2013 Sep 24;73:3.9.1-3.9.9. doi: 10.1002/0471140864.ps0309s73. Curr Protoc Protein Sci. 2013. PMID: 24510594 Free PMC article.
Symmetric Epistasis Estimation (SEE) and its application to dissecting interaction map of Plasmodium falciparum.
Huang Y, Siwo G, Wuchty S, Ferdig MT, Przytycka TM. Huang Y, et al. Among authors: wuchty s. Mol Biosyst. 2012 Apr;8(5):1544-52. doi: 10.1039/c2mb05333k. Epub 2012 Mar 15. Mol Biosyst. 2012. PMID: 22419061 Free PMC article.
We applied our approach to progeny crosses of the human malaria parasite P. falciparum and S. cerevisiae. We found an abundance of epistatic interactions in the parasite and a much smaller number of such interactions in yeast. ...
We applied our approach to progeny crosses of the human malaria parasite P. falciparum and S. cerevisiae. We found an abundance of ep …
Modeling information flow in biological networks.
Kim YA, Przytycki JH, Wuchty S, Przytycka TM. Kim YA, et al. Among authors: wuchty s. Phys Biol. 2011 Jun;8(3):035012. doi: 10.1088/1478-3975/8/3/035012. Epub 2011 May 13. Phys Biol. 2011. PMID: 21572171 Free PMC article. Review.
Genome-wide associations of signaling pathways in glioblastoma multiforme.
Wuchty S, Vazquez A, Bozdag S, Bauer PO. Wuchty S, et al. BMC Med Genomics. 2013 Mar 28;6:11. doi: 10.1186/1755-8794-6-11. BMC Med Genomics. 2013. PMID: 23537212 Free PMC article.
Identifying causal genes and dysregulated pathways in complex diseases.
Kim YA, Wuchty S, Przytycka TM. Kim YA, et al. Among authors: wuchty s. PLoS Comput Biol. 2011 Mar;7(3):e1001095. doi: 10.1371/journal.pcbi.1001095. Epub 2011 Mar 3. PLoS Comput Biol. 2011. PMID: 21390271 Free PMC article.
Graph theoretical approach to study eQTL: a case study of Plasmodium falciparum.
Huang Y, Wuchty S, Ferdig MT, Przytycka TM. Huang Y, et al. Among authors: wuchty s. Bioinformatics. 2009 Jun 15;25(12):i15-20. doi: 10.1093/bioinformatics/btp189. Bioinformatics. 2009. PMID: 19477981 Free PMC article.
Module cover - a new approach to genotype-phenotype studies.
Kim YA, Salari R, Wuchty S, Przytycka TM. Kim YA, et al. Among authors: wuchty s. Pac Symp Biocomput. 2013:135-46. Pac Symp Biocomput. 2013. PMID: 23424119 Free PMC article.
Cancer missense mutations alter binding properties of proteins and their interaction networks.
Nishi H, Tyagi M, Teng S, Shoemaker BA, Hashimoto K, Alexov E, Wuchty S, Panchenko AR. Nishi H, et al. Among authors: wuchty s. PLoS One. 2013 Jun 14;8(6):e66273. doi: 10.1371/journal.pone.0066273. Print 2013. PLoS One. 2013. PMID: 23799087 Free PMC article.
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