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A mouse for all reasons.
International Mouse Knockout Consortium, Collins FS, Rossant J, Wurst W. International Mouse Knockout Consortium, et al. Cell. 2007 Jan 12;128(1):9-13. doi: 10.1016/j.cell.2006.12.018. Cell. 2007. PMID: 17218247
The mammalian gene function resource: the International Knockout Mouse Consortium.
Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, Hansen J, Hérault Y, Hicks G, Hörlein A, Houghton R, Hrabé de Angelis M, Huylebroeck D, Iyer V, de Jong PJ, Kadin JA, Kaloff C, Kennedy K, Koutsourakis M, Lloyd KC, Marschall S, Mason J, McKerlie C, McLeod MP, von Melchner H, Moore M, Mujica AO, Nagy A, Nefedov M, Nutter LM, Pavlovic G, Peterson JL, Pollock J, Ramirez-Solis R, Rancourt DE, Raspa M, Remacle JE, Ringwald M, Rosen B, Rosenthal N, Rossant J, Ruiz Noppinger P, Ryder E, Schick JZ, Schnütgen F, Schofield P, Seisenberger C, Selloum M, Simpson EM, Skarnes WC, Smedley D, Stanford WL, Stewart AF, Stone K, Swan K, Tadepally H, Teboul L, Tocchini-Valentini GP, Valenzuela D, West AP, Yamamura K, Yoshinaga Y, Wurst W. Bradley A, et al. Mamm Genome. 2012 Oct;23(9-10):580-6. doi: 10.1007/s00335-012-9422-2. Epub 2012 Sep 12. Mamm Genome. 2012. PMID: 22968824 Free PMC article.
The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour.
Vauti F, Goller T, Beine R, Becker L, Klopstock T, Hölter SM, Wurst W, Fuchs H, Gailus-Durner V, de Angelis MH, Arnold HH. Vauti F, et al. Gene. 2007 Mar 15;389(2):174-85. doi: 10.1016/j.gene.2006.11.004. Epub 2006 Nov 17. Gene. 2007. PMID: 17198746
Enhanced gene trapping in mouse embryonic stem cells.
Schnütgen F, Hansen J, De-Zolt S, Horn C, Lutz M, Floss T, Wurst W, Noppinger PR, von Melchner H. Schnütgen F, et al. Nucleic Acids Res. 2008 Nov;36(20):e133. doi: 10.1093/nar/gkn603. Epub 2008 Sep 23. Nucleic Acids Res. 2008. PMID: 18812397 Free PMC article.
High-throughput trapping of secretory pathway genes in mouse embryonic stem cells.
De-Zolt S, Schnütgen F, Seisenberger C, Hansen J, Hollatz M, Floss T, Ruiz P, Wurst W, von Melchner H. De-Zolt S, et al. Nucleic Acids Res. 2006 Feb 13;34(3):e25. doi: 10.1093/nar/gnj026. Nucleic Acids Res. 2006. PMID: 16478711 Free PMC article.
A new partner for the international knockout mouse consortium.
Collins FS, Finnell RH, Rossant J, Wurst W. Collins FS, et al. Cell. 2007 Apr 20;129(2):235. doi: 10.1016/j.cell.2007.04.007. Cell. 2007. PMID: 17448981 No abstract available.
Genomewide production of multipurpose alleles for the functional analysis of the mouse genome.
Schnütgen F, De-Zolt S, Van Sloun P, Hollatz M, Floss T, Hansen J, Altschmied J, Seisenberger C, Ghyselinck NB, Ruiz P, Chambon P, Wurst W, von Melchner H. Schnütgen F, et al. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7221-6. doi: 10.1073/pnas.0502273102. Epub 2005 May 3. Proc Natl Acad Sci U S A. 2005. PMID: 15870191 Free PMC article.
Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases.
Meyer M, de Angelis MH, Wurst W, Kühn R. Meyer M, et al. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15022-6. doi: 10.1073/pnas.1009424107. Epub 2010 Aug 4. Proc Natl Acad Sci U S A. 2010. PMID: 20686113 Free PMC article.
EUCOMM--the European conditional mouse mutagenesis program.
Friedel RH, Seisenberger C, Kaloff C, Wurst W. Friedel RH, et al. Brief Funct Genomic Proteomic. 2007 Sep;6(3):180-5. doi: 10.1093/bfgp/elm022. Epub 2007 Oct 29. Brief Funct Genomic Proteomic. 2007. PMID: 17967808
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P. Hansen J, et al. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22. doi: 10.1073/pnas.1633296100. Epub 2003 Aug 6. Proc Natl Acad Sci U S A. 2003. PMID: 12904583 Free PMC article.
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