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EUCOMM--the European conditional mouse mutagenesis program.
Friedel RH, Seisenberger C, Kaloff C, Wurst W. Friedel RH, et al. Brief Funct Genomic Proteomic. 2007 Sep;6(3):180-5. doi: 10.1093/bfgp/elm022. Epub 2007 Oct 29. Brief Funct Genomic Proteomic. 2007. PMID: 17967808
The mouse Pax2(1Neu) mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney.
Favor J, Sandulache R, Neuhäuser-Klaus A, Pretsch W, Chatterjee B, Senft E, Wurst W, Blanquet V, Grimes P, Spörle R, Schughart K. Favor J, et al. Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13870-5. doi: 10.1073/pnas.93.24.13870. Proc Natl Acad Sci U S A. 1996. PMID: 8943028 Free PMC article.
Optimized vector for conditional gene targeting in mouse embryonic stem cells.
Conrad M, Brielmeier M, Wurst W, Bornkamm GW. Conrad M, et al. Biotechniques. 2003 Jun;34(6):1136-8, 1140. doi: 10.2144/03346bm03. Biotechniques. 2003. PMID: 12813877 No abstract available.
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Hansen J, Floss T, Van Sloun P, Füchtbauer EM, Vauti F, Arnold HH, Schnütgen F, Wurst W, von Melchner H, Ruiz P. Hansen J, et al. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22. doi: 10.1073/pnas.1633296100. Epub 2003 Aug 6. Proc Natl Acad Sci U S A. 2003. PMID: 12904583 Free PMC article.
Expression of neurochondrin in the developing and adult mouse brain.
Istvánffy R, Vogt Weisenhorn DM, Floss T, Wurst W. Istvánffy R, et al. Dev Genes Evol. 2004 Apr;214(4):206-9. doi: 10.1007/s00427-004-0396-2. Epub 2004 Mar 9. Dev Genes Evol. 2004. PMID: 15007648
Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region.
Panhuysen M, Vogt Weisenhorn DM, Blanquet V, Brodski C, Heinzmann U, Beisker W, Wurst W. Panhuysen M, et al. Mol Cell Neurosci. 2004 May;26(1):101-11. doi: 10.1016/j.mcn.2004.01.011. Mol Cell Neurosci. 2004. PMID: 15121182
The European dimension for the mouse genome mutagenesis program.
Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, Barbacid M, Berns A, Bradley A, Brown S, Carmeliet P, Chambon P, Cox R, Davidson D, Davies K, Duboule D, Forejt J, Granucci F, Hastie N, de Angelis MH, Jackson I, Kioussis D, Kollias G, Lathrop M, Lendahl U, Malumbres M, von Melchner H, Müller W, Partanen J, Ricciardi-Castagnoli P, Rigby P, Rosen B, Rosenthal N, Skarnes B, Stewart AF, Thornton J, Tocchini-Valentini G, Wagner E, Wahli W, Wurst W. Auwerx J, et al. Nat Genet. 2004 Sep;36(9):925-7. doi: 10.1038/ng0904-925. Nat Genet. 2004. PMID: 15340424 Free PMC article.
Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function.
Conrad M, Jakupoglu C, Moreno SG, Lippl S, Banjac A, Schneider M, Beck H, Hatzopoulos AK, Just U, Sinowatz F, Schmahl W, Chien KR, Wurst W, Bornkamm GW, Brielmeier M. Conrad M, et al. Mol Cell Biol. 2004 Nov;24(21):9414-23. doi: 10.1128/MCB.24.21.9414-9423.2004. Mol Cell Biol. 2004. PMID: 15485910 Free PMC article.
Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development.
Jakupoglu C, Przemeck GK, Schneider M, Moreno SG, Mayr N, Hatzopoulos AK, de Angelis MH, Wurst W, Bornkamm GW, Brielmeier M, Conrad M. Jakupoglu C, et al. Mol Cell Biol. 2005 Mar;25(5):1980-8. doi: 10.1128/MCB.25.5.1980-1988.2005. Mol Cell Biol. 2005. PMID: 15713651 Free PMC article.
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