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Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of rat corpus striatum.
Ulus IH, Wurtman RJ, Mauron C, Blusztajn JK. Ulus IH, et al. Among authors: wurtman rj. Brain Res. 1989 Apr 10;484(1-2):217-27. doi: 10.1016/0006-8993(89)90364-8. Brain Res. 1989. PMID: 2713682
Thyrotropin-releasing hormone (TRH) content of rat striatum: modification by drugs and lesions.
Spindel ER, Pettibone DJ, Wurtman RJ. Spindel ER, et al. Among authors: wurtman rj. Brain Res. 1981 Jul 20;216(2):323-31. doi: 10.1016/0006-8993(81)90134-7. Brain Res. 1981. PMID: 6265032
Enhancement of free fatty acid incorporation into phospholipids by choline plus cytidine.
Knapp S, Wurtman RJ. Knapp S, et al. Among authors: wurtman rj. Brain Res. 1999 Mar 20;822(1-2):52-9. doi: 10.1016/s0006-8993(99)01072-0. Brain Res. 1999. PMID: 10082883
Evidence for the existence of pyrimidinergic transmission in rat brain.
Cansev M, Orhan F, Yaylagul EO, Isik E, Turkyilmaz M, Aydin S, Gumus A, Sevinc C, Coskun N, Ulus IH, Wurtman RJ. Cansev M, et al. Among authors: wurtman rj. Neuropharmacology. 2015 Apr;91:77-86. doi: 10.1016/j.neuropharm.2014.12.019. Epub 2014 Dec 23. Neuropharmacology. 2015. PMID: 25541414
Cytidine and uridine increase striatal CDP-choline levels without decreasing acetylcholine synthesis or release.
Ulus IH, Watkins CJ, Cansev M, Wurtman RJ. Ulus IH, et al. Among authors: wurtman rj. Cell Mol Neurobiol. 2006 Jul-Aug;26(4-6):563-77. doi: 10.1007/s10571-006-9004-5. Epub 2006 Apr 25. Cell Mol Neurobiol. 2006. PMID: 16636900
Dietary supplementation with uridine-5'-monophosphate (UMP), a membrane phosphatide precursor, increases acetylcholine level and release in striatum of aged rat.
Wang L, Albrecht MA, Wurtman RJ. Wang L, et al. Among authors: wurtman rj. Brain Res. 2007 Feb 16;1133(1):42-8. doi: 10.1016/j.brainres.2006.11.048. Epub 2006 Dec 19. Brain Res. 2007. PMID: 17184749 Free PMC article.
Oral uridine-5'-monophosphate (UMP) increases brain CDP-choline levels in gerbils.
Cansev M, Watkins CJ, van der Beek EM, Wurtman RJ. Cansev M, et al. Among authors: wurtman rj. Brain Res. 2005 Oct 5;1058(1-2):101-8. doi: 10.1016/j.brainres.2005.07.054. Epub 2005 Aug 29. Brain Res. 2005. PMID: 16126180
Stimulation of CDP-choline synthesis by uridine or cytidine in PC12 rat pheochromocytoma cells.
Richardson UI, Watkins CJ, Pierre C, Ulus IH, Wurtman RJ. Richardson UI, et al. Among authors: wurtman rj. Brain Res. 2003 May 9;971(2):161-7. doi: 10.1016/s0006-8993(03)02333-3. Brain Res. 2003. PMID: 12706232
Platelet-activating factor increases prostaglandin E(2) release from astrocyte-enriched cortical cell cultures.
Teather LA, Lee RK, Wurtman RJ. Teather LA, et al. Among authors: wurtman rj. Brain Res. 2002 Aug 9;946(1):87-95. doi: 10.1016/s0006-8993(02)02866-4. Brain Res. 2002. PMID: 12133598
Synaptic proteins and phospholipids are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally.
Wurtman RJ, Ulus IH, Cansev M, Watkins CJ, Wang L, Marzloff G. Wurtman RJ, et al. Brain Res. 2006 May 9;1088(1):83-92. doi: 10.1016/j.brainres.2006.03.019. Epub 2006 Apr 21. Brain Res. 2006. PMID: 16631143
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