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Drug Discovery in Academia- the third way?
Frearson J, Wyatt P. Frearson J, et al. Among authors: wyatt p. Expert Opin Drug Discov. 2010 Oct 1;5(10):909-19. doi: 10.1517/17460441.2010.506508. Expert Opin Drug Discov. 2010. PMID: 20922062 Free PMC article.
Target assessment for antiparasitic drug discovery.
Frearson JA, Wyatt PG, Gilbert IH, Fairlamb AH. Frearson JA, et al. Trends Parasitol. 2007 Dec;23(12):589-95. doi: 10.1016/j.pt.2007.08.019. Epub 2007 Oct 24. Trends Parasitol. 2007. PMID: 17962072 Free PMC article. Review.
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.
Frearson JA, Brand S, McElroy SP, Cleghorn LA, Smid O, Stojanovski L, Price HP, Guther ML, Torrie LS, Robinson DA, Hallyburton I, Mpamhanga CP, Brannigan JA, Wilkinson AJ, Hodgkinson M, Hui R, Qiu W, Raimi OG, van Aalten DM, Brenk R, Gilbert IH, Read KD, Fairlamb AH, Ferguson MA, Smith DF, Wyatt PG. Frearson JA, et al. Among authors: wyatt pg. Nature. 2010 Apr 1;464(7289):728-32. doi: 10.1038/nature08893. Nature. 2010. PMID: 20360736 Free PMC article.
Dihydroquinazolines as a novel class of Trypanosoma brucei trypanothione reductase inhibitors: discovery, synthesis, and characterization of their binding mode by protein crystallography.
Patterson S, Alphey MS, Jones DC, Shanks EJ, Street IP, Frearson JA, Wyatt PG, Gilbert IH, Fairlamb AH. Patterson S, et al. Among authors: wyatt pg. J Med Chem. 2011 Oct 13;54(19):6514-30. doi: 10.1021/jm200312v. Epub 2011 Sep 1. J Med Chem. 2011. PMID: 21851087 Free PMC article.
286 results