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98 results
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A biosensor-based approach toward purification and crystallization of G protein-coupled receptors.
Navratilova I, Pancera M, Wyatt RT, Myszka DG. Navratilova I, et al. Among authors: wyatt rt. Anal Biochem. 2006 Jun 15;353(2):278-83. doi: 10.1016/j.ab.2006.03.049. Epub 2006 Apr 18. Anal Biochem. 2006. PMID: 16647033
Antibody 17b binding at the coreceptor site weakens the kinetics of the interaction of envelope glycoprotein gp120 with CD4.
Zhang W, Godillot AP, Wyatt R, Sodroski J, Chaiken I. Zhang W, et al. Biochemistry. 2001 Feb 13;40(6):1662-70. doi: 10.1021/bi001397m. Biochemistry. 2001. PMID: 11327825
Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic.
Zhang W, Canziani G, Plugariu C, Wyatt R, Sodroski J, Sweet R, Kwong P, Hendrickson W, Chaiken I. Zhang W, et al. Biochemistry. 1999 Jul 20;38(29):9405-16. doi: 10.1021/bi990654o. Biochemistry. 1999. PMID: 10413516
Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1).
Kwong PD, Wyatt R, Desjardins E, Robinson J, Culp JS, Hellmig BD, Sweet RW, Sodroski J, Hendrickson WA. Kwong PD, et al. J Biol Chem. 1999 Feb 12;274(7):4115-23. doi: 10.1074/jbc.274.7.4115. J Biol Chem. 1999. PMID: 9933605
Energetics of the HIV gp120-CD4 binding reaction.
Myszka DG, Sweet RW, Hensley P, Brigham-Burke M, Kwong PD, Hendrickson WA, Wyatt R, Sodroski J, Doyle ML. Myszka DG, et al. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9026-31. doi: 10.1073/pnas.97.16.9026. Proc Natl Acad Sci U S A. 2000. PMID: 10922058 Free PMC article.
Enhanced expression, native purification, and characterization of CCR5, a principal HIV-1 coreceptor.
Mirzabekov T, Bannert N, Farzan M, Hofmann W, Kolchinsky P, Wu L, Wyatt R, Sodroski J. Mirzabekov T, et al. J Biol Chem. 1999 Oct 1;274(40):28745-50. doi: 10.1074/jbc.274.40.28745. J Biol Chem. 1999. PMID: 10497246
Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4.
Huang CC, Lam SN, Acharya P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CA, Kwong PD. Huang CC, et al. Science. 2007 Sep 28;317(5846):1930-4. doi: 10.1126/science.1145373. Science. 2007. PMID: 17901336 Free PMC article.
Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Zhou T, Xu L, Dey B, Hessell AJ, Van Ryk D, Xiang SH, Yang X, Zhang MY, Zwick MB, Arthos J, Burton DR, Dimitrov DS, Sodroski J, Wyatt R, Nabel GJ, Kwong PD. Zhou T, et al. Nature. 2007 Feb 15;445(7129):732-7. doi: 10.1038/nature05580. Nature. 2007. PMID: 17301785 Free PMC article.
Tyrosine-sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry.
Lam SN, Acharya P, Wyatt R, Kwong PD, Bewley CA. Lam SN, et al. Bioorg Med Chem. 2008 Dec 1;16(23):10113-20. doi: 10.1016/j.bmc.2008.10.005. Epub 2008 Oct 5. Bioorg Med Chem. 2008. PMID: 18952441 Free PMC article.
Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein.
Xiang SH, Kwong PD, Gupta R, Rizzuto CD, Casper DJ, Wyatt R, Wang L, Hendrickson WA, Doyle ML, Sodroski J. Xiang SH, et al. J Virol. 2002 Oct;76(19):9888-99. doi: 10.1128/jvi.76.19.9888-9899.2002. J Virol. 2002. PMID: 12208966 Free PMC article.
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