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Wychimicins E and F from a rare actinomycete of the genus Cryptosporangium.
Triningsih DW, Yoshizaki N, Igarashi Y. Triningsih DW, et al. J Antibiot (Tokyo). 2024 Dec;77(12):847-851. doi: 10.1038/s41429-024-00770-y. Epub 2024 Sep 3. J Antibiot (Tokyo). 2024. PMID: 39227690
Two new spirotetronate class compounds designated wychimicins E (1) and F (2) were isolated from the culture extract of an actinomycete Cryptosporangium sp. ...
Two new spirotetronate class compounds designated wychimicins E (1) and F (2) were isolated from the culture extract of an actinomyce …
Wychimicins, a new class of spirotetronate polyketides from Actinocrispum wychmicini MI503-A4.
Kimura T, Umekita M, Hatano M, Hayashi C, Sawa R, Igarashi M. Kimura T, et al. J Antibiot (Tokyo). 2022 Oct;75(10):535-541. doi: 10.1038/s41429-022-00560-4. Epub 2022 Sep 7. J Antibiot (Tokyo). 2022. PMID: 36071214 Free PMC article.
Wychimicins are spirotetronates possessing a macrocyclic 13-membered ring containing trans-decalin and beta-D-xylo-hexopyranose moieties connected to C-17 by an O-glycosidic linkage according to MS, NMR and X-ray analyses. ...The stereochemistry of the spirocarbon C-25 was
Wychimicins are spirotetronates possessing a macrocyclic 13-membered ring containing trans-decalin and beta-D-xylo-hexopyranose moiet