Wymann MP - Search Results

1

Lipid signalling in disease.

Wymann MP, Schneiter R. Wymann MP, et al. Nat Rev Mol Cell Biol. 2008 Feb;9(2):162-76. doi: 10.1038/nrm2335. Nat Rev Mol Cell Biol. 2008. PMID: 18216772 Review.

2

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction.

Wymann MP, Bulgarelli-Leva G, Zvelebil MJ, Pirola L, Vanhaesebroeck B, Waterfield MD, Panayotou G. Wymann MP, et al. Mol Cell Biol. 1996 Apr;16(4):1722-33. doi: 10.1128/MCB.16.4.1722. Mol Cell Biol. 1996. PMID: 8657148 Free PMC article.

3

GTPgammaS-induced actin polymerisation in vitro: ATP- and phosphoinositide-independent signalling via Rho-family proteins and a plasma membrane-associated guanine nucleotide exchange factor.

Katanaev VL, Wymann MP. Katanaev VL, et al. Among authors: wymann mp. J Cell Sci. 1998 Jun;111 ( Pt 11):1583-94. doi: 10.1242/jcs.111.11.1583. J Cell Sci. 1998. PMID: 9580566

4

Phosphoinositide 3-kinase signalling: no lipids.

Wymann MP, Pirola L, Katanaev VL, Bulgarelli-Leva G. Wymann MP, et al. Biochem Soc Trans. 1999 Aug;27(4):629-34. doi: 10.1042/bst0270629. Biochem Soc Trans. 1999. PMID: 10917655 Review. No abstract available.

5

Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase alpha (PI3Kalpha ). Functions of lipid kinase-deficient PI3Kalpha in signaling.

Pirola L, Zvelebil MJ, Bulgarelli-Leva G, Van Obberghen E, Waterfield MD, Wymann MP. Pirola L, et al. Among authors: wymann mp. J Biol Chem. 2001 Jun 15;276(24):21544-54. doi: 10.1074/jbc.M011330200. Epub 2001 Feb 13. J Biol Chem. 2001. PMID: 11278889

6

Tumour biology. Weakening link to colorectal cancer?

Barbier M, Attoub S, Calvez R, Laffargue M, Jarry A, Mareel M, Altruda F, Gespach C, Wu D, Lu B, Hirsch E, Wymann MP. Barbier M, et al. Among authors: wymann mp. Nature. 2001 Oct 25;413(6858):796. doi: 10.1038/35101660. Nature. 2001. PMID: 11677595 No abstract available.

7

Phosphoinositide 3-kinase gamma: a key modulator in inflammation and allergy.

Wymann MP, Björklöf K, Calvez R, Finan P, Thomast M, Trifilieff A, Barbier M, Altruda F, Hirsch E, Laffargue M. Wymann MP, et al. Biochem Soc Trans. 2003 Feb;31(Pt 1):275-80. doi: 10.1042/bst0310275. Biochem Soc Trans. 2003. PMID: 12546701 Review.

8

Phosphoinositide 3-kinase signalling--which way to target?

Wymann MP, Zvelebil M, Laffargue M. Wymann MP, et al. Trends Pharmacol Sci. 2003 Jul;24(7):366-76. doi: 10.1016/S0165-6147(03)00163-9. Trends Pharmacol Sci. 2003. PMID: 12871670 Review. No abstract available.

9

PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects.

Patrucco E, Notte A, Barberis L, Selvetella G, Maffei A, Brancaccio M, Marengo S, Russo G, Azzolino O, Rybalkin SD, Silengo L, Altruda F, Wetzker R, Wymann MP, Lembo G, Hirsch E. Patrucco E, et al. Among authors: wymann mp. Cell. 2004 Aug 6;118(3):375-87. doi: 10.1016/j.cell.2004.07.017. Cell. 2004. PMID: 15294162

10

The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation.

Solinas G, Summermatter S, Mainieri D, Gubler M, Pirola L, Wymann MP, Rusconi S, Montani JP, Seydoux J, Dulloo AG. Solinas G, et al. Among authors: wymann mp. FEBS Lett. 2004 Nov 19;577(3):539-44. doi: 10.1016/j.febslet.2004.10.066. FEBS Lett. 2004. PMID: 15556643

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