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236 results
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Fibrotic disease and the T(H)1/T(H)2 paradigm.
Wynn TA. Wynn TA. Nat Rev Immunol. 2004 Aug;4(8):583-94. doi: 10.1038/nri1412. Nat Rev Immunol. 2004. PMID: 15286725 Free PMC article. Review.
Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor alpha required as a costimulatory factor for interferon gamma-induced activation.
Oswald IP, Wynn TA, Sher A, James SL. Oswald IP, et al. Among authors: wynn ta. Proc Natl Acad Sci U S A. 1992 Sep 15;89(18):8676-80. doi: 10.1073/pnas.89.18.8676. Proc Natl Acad Sci U S A. 1992. PMID: 1528880 Free PMC article.
Elevated expression of Th1 cytokines and nitric oxide synthase in the lungs of vaccinated mice after challenge infection with Schistosoma mansoni.
Wynn TA, Oswald IP, Eltoum IA, Caspar P, Lowenstein CJ, Lewis FA, James SL, Sher A. Wynn TA, et al. J Immunol. 1994 Dec 1;153(11):5200-9. J Immunol. 1994. PMID: 7525727
An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection.
Wynn TA, Cheever AW, Jankovic D, Poindexter RW, Caspar P, Lewis FA, Sher A. Wynn TA, et al. Nature. 1995 Aug 17;376(6541):594-6. doi: 10.1038/376594a0. Nature. 1995. PMID: 7637808
IL-12 exacerbates rather than suppresses T helper 2-dependent pathology in the absence of endogenous IFN-gamma.
Wynn TA, Jankovic D, Hieny S, Zioncheck K, Jardieu P, Cheever AW, Sher A. Wynn TA, et al. J Immunol. 1995 Apr 15;154(8):3999-4009. J Immunol. 1995. PMID: 7706739
IL-12 enhances vaccine-induced immunity to Schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production, and tissue eosinophilia.
Wynn TA, Jankovic D, Hieny S, Cheever AW, Sher A. Wynn TA, et al. J Immunol. 1995 May 1;154(9):4701-9. J Immunol. 1995. PMID: 7722323
IL-12 inhibits Th2 cytokine responses induced by eggs of Schistosoma mansoni.
Oswald IP, Caspar P, Jankovic D, Wynn TA, Pearce EJ, Sher A. Oswald IP, et al. Among authors: wynn ta. J Immunol. 1994 Aug 15;153(4):1707-13. J Immunol. 1994. PMID: 7913944
Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis.
Cheever AW, Williams ME, Wynn TA, Finkelman FD, Seder RA, Cox TM, Hieny S, Caspar P, Sher A. Cheever AW, et al. Among authors: wynn ta. J Immunol. 1994 Jul 15;153(2):753-9. J Immunol. 1994. PMID: 8021510
Regulatory and immunopathological roles of IL4 in experimental schistosomiasis.
Oswald IP, Wynn TA, Williams ME, Eltoum I, Cheever AW, James SL, Sher A. Oswald IP, et al. Among authors: wynn ta. Res Immunol. 1993 Oct;144(8):643-8. doi: 10.1016/s0923-2494(05)80020-3. Res Immunol. 1993. PMID: 8303083 Review. No abstract available.
IL12 as an adjuvant for vaccines designed to prevent infection and immunopathology by schistosomes.
Wynn TA, Sher A. Wynn TA, et al. Res Immunol. 1995 Sep-Oct;146(7-8):582-90. doi: 10.1016/0923-2494(96)83035-5. Res Immunol. 1995. PMID: 8839165 Review. No abstract available.
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