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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
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1995 11
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1998 15
1999 28
2000 20
2001 22
2002 40
2003 31
2004 15
2005 8
2006 5
2007 10
2008 13
2009 8
2010 3
2011 12
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2014 15
2015 19
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451 results

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Page 1
DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis.
Kim JH, Park SY, Jeon SE, Choi JH, Lee CJ, Jang TY, Yun HJ, Lee Y, Kim P, Cho SH, Lee JS, Nam JS. Kim JH, et al. Theranostics. 2022 Jul 4;12(12):5258-5271. doi: 10.7150/thno.72037. eCollection 2022. Theranostics. 2022. PMID: 35910805 Free PMC article.
Rationale: Doublecortin-like kinase 1 (DCLK1) is a serine/threonine kinase that selectively marks cancer stem-like cells (CSCs) and promotes malignant progression in colorectal cancer (CRC). However, the exact molecular mechanism by which DCLK1 drives the aggressive …
Rationale: Doublecortin-like kinase 1 (DCLK1) is a serine/threonine kinase that selectively marks cancer stem-like cells (CSCs) and p …
Association between XRCC5, 6 and 7 gene polymorphisms and the risk of breast cancer: a HuGE review and meta-analysis.
Zhou LP, Luan H, Dong XH, Jin GJ, Man DL, Shang H. Zhou LP, et al. Asian Pac J Cancer Prev. 2012;13(8):3637-43. doi: 10.7314/apjcp.2012.13.8.3637. Asian Pac J Cancer Prev. 2012. PMID: 23098447 Free article. Review.
OBJECTIVE: Non-homologous end joining (NHEJ) is a pathway for repairing DNA double-strand breaks. Recent publications indicated that XRCC5, XRCC6 and XRCC7 genes may participate in the pathogenesis of breast cancer. The aim of this Human Genome Epidemiology (HuGE) r …
OBJECTIVE: Non-homologous end joining (NHEJ) is a pathway for repairing DNA double-strand breaks. Recent publications indicated that XRCC …
Targeting the radiation-induced ARv7-mediated circNHS/miR-512-5p/XRCC5 signaling with Quercetin increases prostate cancer radiosensitivity.
Chen D, Chou FJ, Chen Y, Huang CP, Tian H, Wang Y, Niu Y, You B, Yeh S, Xing N, Chang C. Chen D, et al. J Exp Clin Cancer Res. 2022 Aug 3;41(1):235. doi: 10.1186/s13046-022-02287-4. J Exp Clin Cancer Res. 2022. PMID: 35918767 Free PMC article.
BACKGROUND: Radiation therapy (RT) with androgen deprivation therapy (ADT) is an effective therapy to suppress the locally advanced prostate cancer (PCa). However, we unexpectedly found that RT could also induce the androgen receptor splice variant 7 (ARv7) expression to d …
BACKGROUND: Radiation therapy (RT) with androgen deprivation therapy (ADT) is an effective therapy to suppress the locally advanced prostate …
Genetic association of XRCC5 gene polymorphisms with breast cancer among Jordanian women.
Al-Eitan LN, Rababa'h DM, Alghamdi MA, Khasawneh RH. Al-Eitan LN, et al. Onco Targets Ther. 2019 Sep 26;12:7923-7928. doi: 10.2147/OTT.S220226. eCollection 2019. Onco Targets Ther. 2019. PMID: 31920325 Free PMC article.
PURPOSE: Breast cancer (BC) is a complex disease that is governed by several different environmental and inherited factors. ...In this study, we aim to investigate the correlation between Variable Number Tandem Repeat (VNTR) in XRCC5 gene and BC. MATERIALS AND METHO …
PURPOSE: Breast cancer (BC) is a complex disease that is governed by several different environmental and inherited factors. ...In thi …
XRCC5/6 polymorphisms and their interactions with smoking, alcohol consumption, and sleep satisfaction in breast cancer risk: A Chinese multi-center study.
Yu LX, Liu LY, Xiang YJ, Wang F, Zhou F, Huang SY, Zheng C, Ye CM, Zhou WZ, Yin GS, Zhang JL, Cui SD, Tian FG, Fan ZM, Geng CZ, Cao XC, Yang ZL, Wang X, Liang H, Wang S, Jiang HC, Duan XN, Wang HB, Li GL, Wang QT, Zhang JG, Jin F, Tang JH, Li L, Zhu SG, Zuo WS, Ma ZB, Yu ZG. Yu LX, et al. Cancer Med. 2021 Apr;10(8):2752-2762. doi: 10.1002/cam4.3847. Epub 2021 Mar 18. Cancer Med. 2021. PMID: 33734613 Free PMC article.
METHODS: The study included 1039 patients with breast cancer and 1040 controls. Four single-nucleotide polymorphisms of XRCC5 and two of XRCC6 were genotyped. ...However, these interactions became insignificant after Bonferroni correction. CONCLUSION: XRCC5 r …
METHODS: The study included 1039 patients with breast cancer and 1040 controls. Four single-nucleotide polymorphisms of XRCC5 …
RUSC1-AS1 promotes the malignant progression of breast cancer depending on the regulation of the miR-326/XRCC5 pathway.
Ayoufu A, Paierhati P, Qiao L, Zhang N, Abudukeremu M. Ayoufu A, et al. Thorac Cancer. 2023 Aug;14(24):2504-2514. doi: 10.1111/1759-7714.15035. Epub 2023 Jul 10. Thorac Cancer. 2023. PMID: 37429610 Free PMC article.
BACKGROUND: Many long noncoding RNAs (lncRNAs) are the key regulators for cancer progression, including breast cancer (BC). RUSC1 antisense 1 (RUSC1-AS1) has been found to be highly expressed in BC, but its role and potential molecular mechanism in BC remain to be f …
BACKGROUND: Many long noncoding RNAs (lncRNAs) are the key regulators for cancer progression, including breast cancer (BC). RU …
Centromeric protein K (CENPK) promotes gastric cancer proliferation and migration via interacting with XRCC5.
Tian H, Wang F, Deng Y, Ying L, Fang W, Chen D, Miao C, Li H, Sun S, Ma Y, Cai H, Guo T. Tian H, et al. Gastric Cancer. 2022 Sep;25(5):879-895. doi: 10.1007/s10120-022-01311-y. Epub 2022 Jun 17. Gastric Cancer. 2022. PMID: 35715658
However, the role and mechanisms of CENPK in gastric cancer have not been explored. METHODS: In this study, we use RT-PCR and IHC to study CENPK expression in gastric cancer cells and tissues. ...Remarkably, we found for the first time that XRCC5 might be int …
However, the role and mechanisms of CENPK in gastric cancer have not been explored. METHODS: In this study, we use RT-PCR and IHC to …
Overexpression of CLC-3 is regulated by XRCC5 and is a poor prognostic biomarker for gastric cancer.
Gu Z, Li Y, Yang X, Yu M, Chen Z, Zhao C, Chen L, Wang L. Gu Z, et al. J Hematol Oncol. 2018 Sep 14;11(1):115. doi: 10.1186/s13045-018-0660-y. J Hematol Oncol. 2018. PMID: 30217218 Free PMC article.
The mechanistic study revealed that knockdown of XRCC5 suppressed the binding of XRCC5 to the CLC-3 promoter and subsequent promoter activity, thus regulating CLC-3 expression at the transcriptional level by interacting with PARP1. CONCLUSIONS: Our findings indicate …
The mechanistic study revealed that knockdown of XRCC5 suppressed the binding of XRCC5 to the CLC-3 promoter and subsequent pr …
SNORD88B-mediated WRN nucleolar trafficking drives self-renewal in liver cancer initiating cells and hepatocarcinogenesis.
Gu Y, Yi Z, Zhou Z, Wang J, Li S, Zhu P, Liu N, Xu Y, He L, Wang Y, Fan Z. Gu Y, et al. Nat Commun. 2024 Aug 7;15(1):6730. doi: 10.1038/s41467-024-50987-6. Nat Commun. 2024. PMID: 39112443 Free PMC article.
Whether small nucleolar RNAs (snoRNAs) are involved in the regulation of liver cancer stem cells (CSCs) self-renewal and serve as therapeutic targets remains largely unclear. ...Mechanistically, SNORD88B anchors WRN in the nucleolus, promoting XRCC5 interacts with S …
Whether small nucleolar RNAs (snoRNAs) are involved in the regulation of liver cancer stem cells (CSCs) self-renewal and serve as the …
miR-623 suppresses cell proliferation, migration and invasion through direct inhibition of XRCC5 in breast cancer.
Li Q, Liu J, Jia Y, Li T, Zhang M. Li Q, et al. Aging (Albany NY). 2020 Jun 5;12(11):10246-10258. doi: 10.18632/aging.103182. Epub 2020 Jun 5. Aging (Albany NY). 2020. PMID: 32501811 Free PMC article.
Results of the reporter assay revealed that the luciferase activity was decreased in XRCC5-wt cells, suggesting that miR-623 could directly combine with 3' UTR of XRCC5. MiR-623 significantly suppressed XRCC5 expression, which is critical for miR-623-induced …
Results of the reporter assay revealed that the luciferase activity was decreased in XRCC5-wt cells, suggesting that miR-623 could di …
451 results