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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1999 2
2000 6
2001 4
2002 2
2003 4
2004 6
2005 25
2006 12
2007 12
2008 18
2009 14
2010 24
2011 19
2012 29
2013 25
2014 17
2015 24
2016 24
2017 32
2018 32
2019 41
2020 27
2021 37
2022 12
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391 results
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Page 1
Reductive Metabolism of Xanthohumol and 8-Prenylnaringenin by the Intestinal Bacterium Eubacterium ramulus.
Paraiso IL, Plagmann LS, Yang L, Zielke R, Gombart AF, Maier CS, Sikora AE, Blakemore PR, Stevens JF. Paraiso IL, et al. Mol Nutr Food Res. 2019 Jan;63(2):e1800923. doi: 10.1002/mnfr.201800923. Epub 2018 Dec 3. Mol Nutr Food Res. 2019. PMID: 30471194 Free PMC article.
Microbial catabolites of polyphenols can contribute in significant ways to the health-promoting properties of their parent polyphenols. This work aims to identify intestinal metabolites of xanthohumol (XN), a prenylated flavonoid found in hops (Humulus lupulus) and beer, a …
Microbial catabolites of polyphenols can contribute in significant ways to the health-promoting properties of their parent polyphenols. This …
Improvements in Metabolic Syndrome by Xanthohumol Derivatives Are Linked to Altered Gut Microbiota and Bile Acid Metabolism.
Zhang Y, Bobe G, Revel JS, Rodrigues RR, Sharpton TJ, Fantacone ML, Raslan K, Miranda CL, Lowry MB, Blakemore PR, Morgun A, Shulzhenko N, Maier CS, Stevens JF, Gombart AF. Zhang Y, et al. Mol Nutr Food Res. 2020 Jan;64(1):e1900789. doi: 10.1002/mnfr.201900789. Epub 2019 Dec 15. Mol Nutr Food Res. 2020. PMID: 31755244 Free PMC article.
SCOPE: Two hydrogenated xanthohumol (XN) derivatives, alpha,beta-dihydro-XN (DXN) and tetrahydro-XN (TXN), improved parameters of metabolic syndrome (MetS), a critical risk factor of cardiovascular disease (CVD) and type 2 diabetes, in a diet-induced obese murine mo …
SCOPE: Two hydrogenated xanthohumol (XN) derivatives, alpha,beta-dihydro-XN (DXN) and tetrahydro-XN (TXN), improved parameters of …
Absorption, metabolism, and pharmacokinetic profile of xanthohumol in rats as determined via UPLC-MS/MS.
Bai HH, Xia TS, Jiang YP, Xu WM, Xu PC, Wang NN, Gou XJ, Xin HL. Bai HH, et al. Biopharm Drug Dispos. 2022 Feb;43(1):11-22. doi: 10.1002/bdd.2306. Epub 2021 Dec 27. Biopharm Drug Dispos. 2022. PMID: 34914109
However, the biological fate of xanthohumol in vivo remains unclear. The aim of this study was to investigate the absorption and metabolism of xanthohumol in rats through UPLC-MS/MS. ...Besides, isoxanthohumol was the major metabolites of xanthohumol. …
However, the biological fate of xanthohumol in vivo remains unclear. The aim of this study was to investigate the absorption and m
Editorial: Flavonoids: From Biosynthesis and Metabolism to Health Benefits.
González-Mas MC, Blázquez MA, López-Gresa MP, Mena P, García-Viguera C. González-Mas MC, et al. Front Plant Sci. 2021 Sep 28;12:727043. doi: 10.3389/fpls.2021.727043. eCollection 2021. Front Plant Sci. 2021. PMID: 34650581 Free PMC article. No abstract available.
The Multiple Biological Targets of Hops and Bioactive Compounds.
Bolton JL, Dunlap TL, Hajirahimkhan A, Mbachu O, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM. Bolton JL, et al. Chem Res Toxicol. 2019 Feb 18;32(2):222-233. doi: 10.1021/acs.chemrestox.8b00345. Epub 2019 Jan 22. Chem Res Toxicol. 2019. PMID: 30608650 Free PMC article. Review.
Pharmacokinetic studies revealed that these flavonoids are conjugated rapidly with glucuronic acid. XH also undergoes phase I metabolism in vivo to form IX, 8-PN, and 6-PN. Several hop constituents are responsible for distinct effects linked to multiple biological targets, …
Pharmacokinetic studies revealed that these flavonoids are conjugated rapidly with glucuronic acid. XH also undergoes phase I metabolism
Microbial Conjugation Studies of Licochalcones and Xanthohumol.
Han F, Xiao Y, Lee IS. Han F, et al. Int J Mol Sci. 2021 Jun 26;22(13):6893. doi: 10.3390/ijms22136893. Int J Mol Sci. 2021. PMID: 34206985 Free PMC article.
Microbial conjugation studies of licochalcones (1-4) and xanthohumol (5) were performed by using the fungi Mucor hiemalis and Absidia coerulea. ...These results could contribute to a better understanding of the metabolic fates of licochalcones and xanthohumol
Microbial conjugation studies of licochalcones (1-4) and xanthohumol (5) were performed by using the fungi Mucor hiemalis and Absidia …
Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis.
Lv H, Liu Q, Wen Z, Feng H, Deng X, Ci X. Lv H, et al. Redox Biol. 2017 Aug;12:311-324. doi: 10.1016/j.redox.2017.03.001. Epub 2017 Mar 2. Redox Biol. 2017. PMID: 28285192 Free PMC article.
Abundant natural flavonoids can induce nuclear factor-erythroid 2 related factor 2 (Nrf2) and/or AMP-activated protein kinase (AMPK) activation, which play crucial roles in the amelioration of various inflammation- and oxidative stress-induced diseases, including acute lung injur …
Abundant natural flavonoids can induce nuclear factor-erythroid 2 related factor 2 (Nrf2) and/or AMP-activated protein kinase (AMPK) activat …
Xanthohumol reduces inflammation and cell metabolism in HT29 primary colon cancer cells.
Torrens-Mas M, Alorda-Clara M, Martínez-Vigara M, Roca P, Sastre-Serra J, Oliver J, Pons DG. Torrens-Mas M, et al. Int J Food Sci Nutr. 2022 Jun;73(4):471-479. doi: 10.1080/09637486.2021.2012561. Epub 2021 Dec 8. Int J Food Sci Nutr. 2022. PMID: 34879764
Xanthohumol (XN) is a prenylated flavonoid known for its antioxidant and anti-inflammatory effects and has been studied as an anti-cancer agent. In this study, we aimed at analysing the effect of XN on a primary colorectal adenocarcinoma cell line, HT29, on cell viability,
Xanthohumol (XN) is a prenylated flavonoid known for its antioxidant and anti-inflammatory effects and has been studied as an anti-ca
Xanthohumol from Hop: Hope for cancer prevention and treatment.
Girisa S, Saikia Q, Bordoloi D, Banik K, Monisha J, Daimary UD, Verma E, Ahn KS, Kunnumakkara AB. Girisa S, et al. IUBMB Life. 2021 Aug;73(8):1016-1044. doi: 10.1002/iub.2522. Epub 2021 Jul 6. IUBMB Life. 2021. PMID: 34170599 Review.
The factors such as drug resistance, lack of specificity, and low efficacy of the cancer drugs necessitate developing alternative strategies for the prevention and treatment of this disease. Xanthohumol (XN), a prenylated chalcone present in Hop (Humulus lupulus), has been …
The factors such as drug resistance, lack of specificity, and low efficacy of the cancer drugs necessitate developing alternative strategies …
The Cancer Prevention, Anti-Inflammatory and Anti-Oxidation of Bioactive Phytochemicals Targeting the TLR4 Signaling Pathway.
Chen CY, Kao CL, Liu CM. Chen CY, et al. Int J Mol Sci. 2018 Sep 12;19(9):2729. doi: 10.3390/ijms19092729. Int J Mol Sci. 2018. PMID: 30213077 Free PMC article. Review.
Curcumin, 6-gingerol, 6-shogaol, 1-dehydro-10-gingerdione, epigallocatechin gallate (EGCG), luteolin, quercetin, resveratrol, caffeic acid phenethyl ester, xanthohumol, genistein, berberine, and sulforaphane can inhibit TLR4 activation. ...
Curcumin, 6-gingerol, 6-shogaol, 1-dehydro-10-gingerdione, epigallocatechin gallate (EGCG), luteolin, quercetin, resveratrol, caffeic acid p …
391 results