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A novel human CCAAT/enhancer binding protein gene, C/EBPepsilon, is expressed in cells of lymphoid and myeloid lineages and is localized on chromosome 14q11.2 close to the T-cell receptor alpha/delta locus.
Antonson P, Stellan B, Yamanaka R, Xanthopoulos KG. Antonson P, et al. Genomics. 1996 Jul 1;35(1):30-8. doi: 10.1006/geno.1996.0319. Genomics. 1996. PMID: 8661101
CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing.
Yamanaka R, Kim GD, Radomska HS, Lekstrom-Himes J, Smith LT, Antonson P, Tenen DG, Xanthopoulos KG. Yamanaka R, et al. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6462-7. doi: 10.1073/pnas.94.12.6462. Proc Natl Acad Sci U S A. 1997. PMID: 9177240 Free PMC article.
High level activity of the mouse CCAAT/enhancer binding protein (C/EBP alpha) gene promoter involves autoregulation and several ubiquitous transcription factors.
Legraverend C, Antonson P, Flodby P, Xanthopoulos KG. Legraverend C, et al. Nucleic Acids Res. 1993 Apr 25;21(8):1735-42. doi: 10.1093/nar/21.8.1735. Nucleic Acids Res. 1993. PMID: 8493090 Free PMC article.
Expression of the liver-enriched transcription factors C/EBP alpha, C/EBP beta, HNF-1, and HNF-4 in preneoplastic nodules and hepatocellular carcinoma in rat liver.
Flodby P, Liao DZ, Blanck A, Xanthopoulos KG, Hällström IP. Flodby P, et al. Mol Carcinog. 1995 Feb;12(2):103-9. doi: 10.1002/mc.2940120207. Mol Carcinog. 1995. PMID: 7662115
Myc inhibits CCAAT/enhancer-binding protein alpha-gene expression in HIB-1B hibernoma cells through interactions with the core promoter region.
Antonson P, Pray MG, Jacobsson A, Xanthopoulos KG. Antonson P, et al. Eur J Biochem. 1995 Sep 1;232(2):397-403. doi: 10.1111/j.1432-1033.1995.397zz.x. Eur J Biochem. 1995. PMID: 7556187
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