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Effects of fluoride on DNA damage, S-phase cell-cycle arrest and the expression of NF-kappaB in primary cultured rat hippocampal neurons.
Zhang M, Wang A, Xia T, He P. Zhang M, et al. Among authors: xia t. Toxicol Lett. 2008 Jun 10;179(1):1-5. doi: 10.1016/j.toxlet.2008.03.002. Epub 2008 Mar 18. Toxicol Lett. 2008. PMID: 18485627
Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis.
Zhou G, Tang S, Yang L, Niu Q, Chen J, Xia T, Wang S, Wang M, Zhao Q, Liu L, Li P, Dong L, Yang K, Zhang S, Wang A. Zhou G, et al. Among authors: xia t. Toxicol Appl Pharmacol. 2019 Sep 1;378:114608. doi: 10.1016/j.taap.2019.114608. Epub 2019 Jun 5. Toxicol Appl Pharmacol. 2019. PMID: 31173788
Modifying effect of COMT gene polymorphism and a predictive role for proteomics analysis in children's intelligence in endemic fluorosis area in Tianjin, China.
Zhang S, Zhang X, Liu H, Qu W, Guan Z, Zeng Q, Jiang C, Gao H, Zhang C, Lei R, Xia T, Wang Z, Yang L, Chen Y, Wu X, Cui Y, Yu L, Wang A. Zhang S, et al. Among authors: xia t. Toxicol Sci. 2015 Apr;144(2):238-45. doi: 10.1093/toxsci/kfu311. Epub 2015 Jan 1. Toxicol Sci. 2015. PMID: 25556215
ERK1/2-mediated disruption of BDNF-TrkB signaling causes synaptic impairment contributing to fluoride-induced developmental neurotoxicity.
Chen J, Niu Q, Xia T, Zhou G, Li P, Zhao Q, Xu C, Dong L, Zhang S, Wang A. Chen J, et al. Among authors: xia t. Toxicology. 2018 Dec 1;410:222-230. doi: 10.1016/j.tox.2018.08.009. Epub 2018 Aug 18. Toxicology. 2018. PMID: 30130557
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
Li P, Liu L, Zhou G, Tian Z, Luo C, Xia T, Chen J, Niu Q, Dong L, Zhao Q, Wang A, Zhang S. Li P, et al. Among authors: xia t. Sci Total Environ. 2018 Dec 15;645:363-371. doi: 10.1016/j.scitotenv.2018.07.138. Epub 2018 Jul 17. Sci Total Environ. 2018. PMID: 30029115
The Pivotal Role of Ca2+ Homeostasis in PBDE-47-Induced Neuronal Apoptosis.
Zhang S, Chen Y, Wu X, Gao H, Ma R, Jiang C, Kuang G, Zhao G, Xia T, Zhang X, Lei R, Zhang C, Li P, Xu C, Wang A. Zhang S, et al. Among authors: xia t. Mol Neurobiol. 2016 Dec;53(10):7078-7088. doi: 10.1007/s12035-015-9573-8. Epub 2015 Dec 17. Mol Neurobiol. 2016. PMID: 26676572
Involvement of the mitochondrial p53 pathway in PBDE-47-induced SH-SY5Y cells apoptosis and its underlying activation mechanism.
Zhang S, Kuang G, Zhao G, Wu X, Zhang C, Lei R, Xia T, Chen J, Wang Z, Ma R, Li B, Yang L, Wang A. Zhang S, et al. Among authors: xia t. Food Chem Toxicol. 2013 Dec;62:699-706. doi: 10.1016/j.fct.2013.10.008. Epub 2013 Oct 16. Food Chem Toxicol. 2013. PMID: 24140468
The role of the IRE1 pathway in PBDE-47-induced toxicity in human neuroblastoma SH-SY5Y cells in vitro.
Jiang C, Zhang S, Liu H, Zeng Q, Xia T, Chen Y, Kuang G, Zhao G, Wu X, Zhang X, Wang A. Jiang C, et al. Among authors: xia t. Toxicol Lett. 2012 Jun 20;211(3):325-33. doi: 10.1016/j.toxlet.2012.04.009. Epub 2012 Apr 18. Toxicol Lett. 2012. PMID: 22543052
Toxic effect of PBDE-47 on thyroid development, learning, and memory, and the interaction between PBDE-47 and PCB153 that enhances toxicity in rats.
He P, Wang A, Niu Q, Guo L, Xia T, Chen X. He P, et al. Among authors: xia t. Toxicol Ind Health. 2011 Apr;27(3):279-88. doi: 10.1177/0748233710387002. Epub 2010 Oct 14. Toxicol Ind Health. 2011. PMID: 20947653
Concentrations of PBDE-47, triiodothyronine (T(3)), thyroxine (T(4)), and thyroid-stimulating hormone (TSH) in serum; organ-to-body weight ratios; as well as long-term learning and memory were measured in 2-month-old rats. The present study found that some doses of …
Concentrations of PBDE-47, triiodothyronine (T(3)), thyroxine (T(4)), and thyroid-stimulating hormone (TSH) in serum; organ-to …
Mechanisms underlying the developmental neurotoxic effect of PBDE-47 and the enhanced toxicity associated with its combination with PCB153 in rats.
He P, Wang AG, Xia T, Gao P, Niu Q, Guo LJ, Chen XM. He P, et al. Among authors: xia t. Neurotoxicology. 2009 Nov;30(6):1088-95. doi: 10.1016/j.neuro.2009.06.005. Epub 2009 Jul 1. Neurotoxicology. 2009. PMID: 19576244
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