Xiang W - Search Results

1

The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice.

Schreglmann SR, Regensburger M, Rockenstein E, Masliah E, Xiang W, Winkler J, Winner B. Schreglmann SR, et al. Among authors: xiang w. PLoS One. 2015 May 11;10(5):e0126261. doi: 10.1371/journal.pone.0126261. eCollection 2015. PLoS One. 2015. PMID: 25961568 Free PMC article.

2

Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity.

Xiang W, Schlachetzki JC, Helling S, Bussmann JC, Berlinghof M, Schäffer TE, Marcus K, Winkler J, Klucken J, Becker CM. Xiang W, et al. Mol Cell Neurosci. 2013 May;54:71-83. doi: 10.1016/j.mcn.2013.01.004. Epub 2013 Jan 28. Mol Cell Neurosci. 2013. PMID: 23369945

3

Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells.

Ettle B, Reiprich S, Deusser J, Schlachetzki JC, Xiang W, Prots I, Masliah E, Winner B, Wegner M, Winkler J. Ettle B, et al. Among authors: xiang w. Mol Cell Neurosci. 2014 Sep;62:68-78. doi: 10.1016/j.mcn.2014.06.012. Epub 2014 Jul 11. Mol Cell Neurosci. 2014. PMID: 25019582 Free PMC article.

4

Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment.

Poehler AM, Xiang W, Spitzer P, May VE, Meixner H, Rockenstein E, Chutna O, Outeiro TF, Winkler J, Masliah E, Klucken J. Poehler AM, et al. Among authors: xiang w. Autophagy. 2014;10(12):2171-92. doi: 10.4161/auto.36436. Autophagy. 2014. PMID: 25484190 Free PMC article.

5

Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity.

Xiang W, Menges S, Schlachetzki JC, Meixner H, Hoffmann AC, Schlötzer-Schrehardt U, Becker CM, Winkler J, Klucken J. Xiang W, et al. Mol Neurodegener. 2015 Mar 11;10:8. doi: 10.1186/s13024-015-0004-0. Mol Neurodegener. 2015. PMID: 25886189 Free PMC article.

6

Infiltrating T lymphocytes reduce myeloid phagocytosis activity in synucleinopathy model.

Sommer A, Fadler T, Dorfmeister E, Hoffmann AC, Xiang W, Winner B, Prots I. Sommer A, et al. Among authors: xiang w. J Neuroinflammation. 2016 Jun 30;13(1):174. doi: 10.1186/s12974-016-0632-5. J Neuroinflammation. 2016. PMID: 27364890 Free PMC article.

7

Alpha-synuclein activates BV2 microglia dependent on its aggregation state.

Hoffmann A, Ettle B, Bruno A, Kulinich A, Hoffmann AC, von Wittgenstein J, Winkler J, Xiang W, Schlachetzki JCM. Hoffmann A, et al. Among authors: xiang w. Biochem Biophys Res Commun. 2016 Oct 28;479(4):881-886. doi: 10.1016/j.bbrc.2016.09.109. Epub 2016 Sep 22. Biochem Biophys Res Commun. 2016. PMID: 27666480

8

Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress.

Menges S, Minakaki G, Schaefer PM, Meixner H, Prots I, Schlötzer-Schrehardt U, Friedland K, Winner B, Outeiro TF, Winklhofer KF, von Arnim CA, Xiang W, Winkler J, Klucken J. Menges S, et al. Among authors: xiang w. Sci Rep. 2017 Feb 22;7:42942. doi: 10.1038/srep42942. Sci Rep. 2017. PMID: 28224980 Free PMC article.

9

Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice.

Regensburger M, Schreglmann SR, Stoll S, Rockenstein E, Loskarn S, Xiang W, Masliah E, Winner B. Regensburger M, et al. Among authors: xiang w. Brain Struct Funct. 2018 Apr;223(3):1357-1368. doi: 10.1007/s00429-017-1561-5. Epub 2017 Nov 9. Brain Struct Funct. 2018. PMID: 29124353 Free PMC article.

10

Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype.

Minakaki G, Menges S, Kittel A, Emmanouilidou E, Schaeffner I, Barkovits K, Bergmann A, Rockenstein E, Adame A, Marxreiter F, Mollenhauer B, Galasko D, Buzás EI, Schlötzer-Schrehardt U, Marcus K, Xiang W, Lie DC, Vekrellis K, Masliah E, Winkler J, Klucken J. Minakaki G, et al. Among authors: xiang w. Autophagy. 2018;14(1):98-119. doi: 10.1080/15548627.2017.1395992. Epub 2018 Jan 15. Autophagy. 2018. PMID: 29198173 Free PMC article.

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