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Successive passaging of the scrapie strains, ME7-ha and 139A-ha, generated by the interspecies transmission of mouse-adapted strains into hamsters markedly shortens the incubation times, but maintains their molecular and pathological properties.
Shi Q, Xiao K, Zhang BY, Zhang XM, Chen LN, Chen C, Gao C, Dong XP. Shi Q, et al. Among authors: Xiao K. Int J Mol Med. 2015 Apr;35(4):1138-46. doi: 10.3892/ijmm.2015.2102. Epub 2015 Feb 13. Int J Mol Med. 2015. PMID: 25683243
Re-infection of the prion from the scrapie‑infected cell line SMB-S15 in three strains of mice, CD1, C57BL/6 and Balb/c.
Xiao K, Zhang BY, Zhang XM, Wang J, Chen C, Chen LN, Lv Y, Shi Q, Dong XP. Xiao K, et al. Int J Mol Med. 2016 Mar;37(3):716-26. doi: 10.3892/ijmm.2016.2465. Epub 2016 Jan 25. Int J Mol Med. 2016. PMID: 26820255 Free PMC article.
The pathogenic characteristics, such as the electrophoretic and glycosylation profiles and proteinase K (PK) resistance of PrPSc molecules, as well as the neuropathological characteristics, such as spongiform vacuolation, PrPSc deposits in cortex regions, astrogliosis and …
The pathogenic characteristics, such as the electrophoretic and glycosylation profiles and proteinase K (PK) resistance of PrPSc mole …
Clinical and laboratory features of 14 young Chinese probable sCJD patients.
Shi Q, Xiao K, Chen C, Zhou W, Gao C, Wang J, Zhang BY, Wang Y, Dong XP. Shi Q, et al. Among authors: Xiao K. Prion. 2017 Mar 4;11(2):128-135. doi: 10.1080/19336896.2017.1287656. Epub 2017 Mar 9. Prion. 2017. PMID: 28278113 Free PMC article.
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