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Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts.
Lin X, Gupta D, Vaitsiankova A, Bhandari SK, Leung KSK, Menolfi D, Lee BJ, Russell HR, Gershik S, Gu W, McKinnon PJ, Dantzer F, Rothenberg E, Tomkinson AE, Zha S. Lin X, et al. Among authors: zha s. bioRxiv [Preprint]. 2024 Mar 14:2024.03.12.584665. doi: 10.1101/2024.03.12.584665. bioRxiv. 2024. Update in: Mol Cell. 2024 Oct 17;84(20):3916-3931.e7. doi: 10.1016/j.molcel.2024.09.020. PMID: 38559022 Free PMC article. Updated. Preprint.
CtIP is essential for early B cell proliferation and development in mice.
Liu X, Wang XS, Lee BJ, Wu-Baer FK, Lin X, Shao Z, Estes VM, Gautier J, Baer R, Zha S. Liu X, et al. Among authors: zha s, lin x. J Exp Med. 2019 Jul 1;216(7):1648-1663. doi: 10.1084/jem.20181139. Epub 2019 May 16. J Exp Med. 2019. PMID: 31097467 Free PMC article.