Xu H - Search Results

1

Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety.

Ananthan S, Johnson CA, Carter RL, Clayton SD, Rice KC, Xu H, Davis P, Porreca F, Rothman RB. Ananthan S, et al. Among authors: xu h. J Med Chem. 1998 Jul 16;41(15):2872-81. doi: 10.1021/jm980083i. J Med Chem. 1998. PMID: 9667975

2

Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans.

Ananthan S, Kezar HS 3rd, Carter RL, Saini SK, Rice KC, Wells JL, Davis P, Xu H, Dersch CM, Bilsky EJ, Porreca F, Rothman RB. Ananthan S, et al. Among authors: xu h. J Med Chem. 1999 Sep 9;42(18):3527-38. doi: 10.1021/jm990039i. J Med Chem. 1999. PMID: 10479286

3

Probes for narcotic receptor-mediated phenomena. 27. Synthesis and pharmacological evaluation of selective delta-opioid receptor agonists from 4-[(alphaR)-alpha-(2S,5R)-4-substituted-2, 5-dimethyl-1-piperazinyl-3-methoxybenzyl]-N,N-diethylbenzamides and their enantiomers.

Furness MS, Zhang X, Coop A, Jacobson AE, Rothman RB, Dersch CM, Xu H, Porreca F, Rice KC. Furness MS, et al. Among authors: xu h. J Med Chem. 2000 Aug 10;43(16):3193-6. doi: 10.1021/jm0001222. J Med Chem. 2000. PMID: 10956228

4

Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy.

McLamore S, Ullrich T, Rothman RB, Xu H, Dersch C, Coop A, Davis P, Porreca F, Jacobson AE, Rice KC. McLamore S, et al. Among authors: xu h. J Med Chem. 2001 Apr 26;44(9):1471-4. doi: 10.1021/jm000511w. J Med Chem. 2001. PMID: 11311071

5

(E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma 2 receptor subtype.

Bertha CM, Vilner BJ, Mattson MV, Bowen WD, Becketts K, Xu H, Rothman RB, Flippen-Anderson JL, Rice KC. Bertha CM, et al. Among authors: xu h. J Med Chem. 1995 Nov 24;38(24):4776-85. doi: 10.1021/jm00024a005. J Med Chem. 1995. PMID: 7490727

6

Probes for narcotic receptor-mediated phenomena. 20. Alteration of opioid receptor subtype selectivity of the 5-(3-hydroxyphenyl)morphans by application of the message-address concept: preparation of delta-opioid receptor ligands.

Bertha CM, Flippen-Anderson JL, Rothman RB, Porreca F, Davis P, Xu H, Becketts K, Cha XY, Rice KC. Bertha CM, et al. Among authors: xu h. J Med Chem. 1995 Apr 28;38(9):1523-37. doi: 10.1021/jm00009a013. J Med Chem. 1995. PMID: 7739011

7

A marked change of receptor affinity of the 2-methyl-5-(3-hydroxyphenyl)morphans upon attachment of an (E)-8-benzylidene moiety: synthesis and evaluation of a new class of sigma receptor ligands.

Bertha CM, Mattson MV, Flippen-Anderson JL, Rothman RB, Xu H, Cha XY, Becketts K, Rice KC. Bertha CM, et al. Among authors: xu h. J Med Chem. 1994 Sep 16;37(19):3163-70. doi: 10.1021/jm00045a022. J Med Chem. 1994. PMID: 7932540

8

Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)-4-[(alpha R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3- methoxybenzyl]-N,N-diethylbenzamide (SNC 80): a highly selective, nonpeptide delta opioid receptor agonist.

Calderon SN, Rothman RB, Porreca F, Flippen-Anderson JL, McNutt RW, Xu H, Smith LE, Bilsky EJ, Davis P, Rice KC. Calderon SN, et al. Among authors: xu h. J Med Chem. 1994 Jul 8;37(14):2125-8. doi: 10.1021/jm00040a002. J Med Chem. 1994. PMID: 8035418 No abstract available.

9

Probes for narcotic receptor-mediated phenomena. 21. Novel derivatives of 3-(1,2,3,4,5,11-hexahydro-3-methyl-2,6-methano-6H-azocino[4,5-b]indol- 6-yl)-phenols with improved delta opioid receptor selectivity.

Bertha CM, Ellis M, Flippen-Anderson JL, Porreca F, Rothman RB, Davis P, Xu H, Becketts K, Rice KC. Bertha CM, et al. Among authors: xu h. J Med Chem. 1996 May 10;39(10):2081-6. doi: 10.1021/jm950695s. J Med Chem. 1996. PMID: 8642567

10

Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands.

Calderon SN, Rice KC, Rothman RB, Porreca F, Flippen-Anderson JL, Kayakiri H, Xu H, Becketts K, Smith LE, Bilsky EJ, Davis P, Horvath R. Calderon SN, et al. Among authors: xu h. J Med Chem. 1997 Feb 28;40(5):695-704. doi: 10.1021/jm960319n. J Med Chem. 1997. PMID: 9057856

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