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A small-molecule dengue virus entry inhibitor.
Wang QY, Patel SJ, Vangrevelinghe E, Xu HY, Rao R, Jaber D, Schul W, Gu F, Heudi O, Ma NL, Poh MK, Phong WY, Keller TH, Jacoby E, Vasudevan SG. Wang QY, et al. Among authors: xu hy. Antimicrob Agents Chemother. 2009 May;53(5):1823-31. doi: 10.1128/AAC.01148-08. Epub 2009 Feb 17. Antimicrob Agents Chemother. 2009. PMID: 19223625 Free PMC article.
An adenosine nucleoside inhibitor of dengue virus.
Yin Z, Chen YL, Schul W, Wang QY, Gu F, Duraiswamy J, Kondreddi RR, Niyomrattanakit P, Lakshminarayana SB, Goh A, Xu HY, Liu W, Liu B, Lim JY, Ng CY, Qing M, Lim CC, Yip A, Wang G, Chan WL, Tan HP, Lin K, Zhang B, Zou G, Bernard KA, Garrett C, Beltz K, Dong M, Weaver M, He H, Pichota A, Dartois V, Keller TH, Shi PY. Yin Z, et al. Among authors: xu hy. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20435-9. doi: 10.1073/pnas.0907010106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918064 Free PMC article.
Inhibition of dengue virus RNA synthesis by an adenosine nucleoside.
Chen YL, Yin Z, Duraiswamy J, Schul W, Lim CC, Liu B, Xu HY, Qing M, Yip A, Wang G, Chan WL, Tan HP, Lo M, Liung S, Kondreddi RR, Rao R, Gu H, He H, Keller TH, Shi PY. Chen YL, et al. Among authors: xu hy. Antimicrob Agents Chemother. 2010 Jul;54(7):2932-9. doi: 10.1128/AAC.00140-10. Epub 2010 May 10. Antimicrob Agents Chemother. 2010. PMID: 20457821 Free PMC article.
Inhibition of dengue virus by an ester prodrug of an adenosine analog.
Chen YL, Yin Z, Lakshminarayana SB, Qing M, Schul W, Duraiswamy J, Kondreddi RR, Goh A, Xu HY, Yip A, Liu B, Weaver M, Dartois V, Keller TH, Shi PY. Chen YL, et al. Among authors: xu hy. Antimicrob Agents Chemother. 2010 Aug;54(8):3255-61. doi: 10.1128/AAC.00397-10. Epub 2010 Jun 1. Antimicrob Agents Chemother. 2010. PMID: 20516277 Free PMC article.
Inhibition of dengue virus through suppression of host pyrimidine biosynthesis.
Wang QY, Bushell S, Qing M, Xu HY, Bonavia A, Nunes S, Zhou J, Poh MK, Florez de Sessions P, Niyomrattanakit P, Dong H, Hoffmaster K, Goh A, Nilar S, Schul W, Jones S, Kramer L, Compton T, Shi PY. Wang QY, et al. Among authors: xu hy. J Virol. 2011 Jul;85(13):6548-56. doi: 10.1128/JVI.02510-10. Epub 2011 Apr 20. J Virol. 2011. PMID: 21507975 Free PMC article.
A translation inhibitor that suppresses dengue virus in vitro and in vivo.
Wang QY, Kondreddi RR, Xie X, Rao R, Nilar S, Xu HY, Qing M, Chang D, Dong H, Yokokawa F, Lakshminarayana SB, Goh A, Schul W, Kramer L, Keller TH, Shi PY. Wang QY, et al. Among authors: xu hy. Antimicrob Agents Chemother. 2011 Sep;55(9):4072-80. doi: 10.1128/AAC.00620-11. Epub 2011 Jul 5. Antimicrob Agents Chemother. 2011. PMID: 21730119 Free PMC article.
Inhibition of dengue virus by targeting viral NS4B protein.
Xie X, Wang QY, Xu HY, Qing M, Kramer L, Yuan Z, Shi PY. Xie X, et al. Among authors: xu hy. J Virol. 2011 Nov;85(21):11183-95. doi: 10.1128/JVI.05468-11. Epub 2011 Aug 24. J Virol. 2011. PMID: 21865382 Free PMC article.
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